7XAV

Structure of somatostatin receptor 2 bound with lanreotide.

Summary for 7XAV

Entry DOI	10.2210/pdb7xav/pdb
EMDB information	33100
Descriptor	Somatostatin receptor type 2,LargeBit, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	g protein coupled receptor, cryo-em, sst analogues, polypeptide drugs, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	184450.02
Authors	Bo, Q.,Yang, F.,Li, Y.G.,Meng, X.Y.,Zhang, H.H.,Zhou, Y.X.,Ling, S.L.,Sun, D.M.,Lv, P.,Liu, L.,Shi, P.,Tian, C.L. (deposition date: 2022-03-19, release date: 2022-08-31)
Primary citation	Bo, Q.,Yang, F.,Li, Y.,Meng, X.,Zhang, H.,Zhou, Y.,Ling, S.,Sun, D.,Lv, P.,Liu, L.,Shi, P.,Tian, C. Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8:47-47, 2022 Cited by PubMed: 35595746 DOI: 10.1038/s41421-022-00405-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.87 Å)

Structure validation