7RCL
Crystal Structure of ADP-bound Galactokinase
Summary for 7RCL
Entry DOI | 10.2210/pdb7rcl/pdb |
Descriptor | Galactokinase, alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | galk, galactokinase, galactose, adp, disulfide, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 172475.37 |
Authors | Whitby, F.G.,Hall, M.D. (deposition date: 2021-07-07, release date: 2021-09-29, Last modification date: 2023-10-18) |
Primary citation | Liu, L.,Tang, M.,Pragani, R.,Whitby, F.G.,Zhang, Y.Q.,Balakrishnan, B.,Fang, Y.,Karavadhi, S.,Tao, D.,LeClair, C.A.,Hall, M.D.,Marugan, J.J.,Boxer, M.,Shen, M.,Hill, C.P.,Lai, K.,Patnaik, S. Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64:13551-13571, 2021 Cited by PubMed: 34491744DOI: 10.1021/acs.jmedchem.1c00945 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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