7RCM

Crystal Structure of ADP-bound Galactokinase

Summary for 7RCM

• Entry DOI: 10.2210/pdb7rcm/pdb
• Descriptor: Galactokinase, ADENOSINE-5'-DIPHOSPHATE, alpha-D-galactopyranose, ... (8 entities in total)
• Functional Keywords: galk, galactokinase, galactose, adp, disulfide, sugar binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 86377.26

Authors

Whitby, F.G. (deposition date: 2021-07-07, release date: 2021-09-29, Last modification date: 2023-10-18)

• Primary citation: Liu, L.,Tang, M.,Pragani, R.,Whitby, F.G.,Zhang, Y.Q.,Balakrishnan, B.,Fang, Y.,Karavadhi, S.,Tao, D.,LeClair, C.A.,Hall, M.D.,Marugan, J.J.,Boxer, M.,Shen, M.,Hill, C.P.,Lai, K.,Patnaik, S.; Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.; J.Med.Chem., 64:13551-13571, 2021; PubMed: 34491744; DOI: 10.1021/acs.jmedchem.1c00945

Experimental method

X-RAY DIFFRACTION (2.1 Å)