7UDZ

Designed pentameric proton channel LQLL

Summary for 7UDZ

Entry DOI	10.2210/pdb7udz/pdb
Descriptor	De novo designed pentameric proton channel LQLL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate (3 entities in total)
Functional Keywords	proton transport, de novo designed, pentameric, membrane protein
Biological source	synthetic construct
Total number of polymer chains	10
Total formula weight	31527.92
Authors	Kratochvil, H.T.,Thomaston, J.L.,Mravic, M.,Nicoludis, J.M.,Liu, L.,DeGrado, W.F. (deposition date: 2022-03-20, release date: 2022-04-06, Last modification date: 2023-10-25)
Primary citation	Kratochvil, H.T.,Watkins, L.C.,Mravic, M.,Thomaston, J.L.,Nicoludis, J.M.,Somberg, N.H.,Liu, L.,Hong, M.,Voth, G.A.,DeGrado, W.F. Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15:1012-1021, 2023 Cited by PubMed: 37308712 DOI: 10.1038/s41557-023-01210-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation