2G3S
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![BU of 2g3s by Molmil](/molmil-images/mine/2g3s) | RNA structure containing GU base pairs | Descriptor: | 5'-R(*GP*GP*CP*GP*UP*GP*CP*C)-3', MAGNESIUM ION | Authors: | Jang, S.B, Hung, L.W, Jeong, M.S, Holbrook, E.L, Chen, X, Turner, D.H, Holbrook, S.R. | Deposit date: | 2006-02-20 | Release date: | 2007-01-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | The crystal structure at 1.5 angstroms resolution of an RNA octamer duplex containing tandem G.U basepairs Biophys.J., 90, 2006
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2HDC
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![BU of 2hdc by Molmil](/molmil-images/mine/2hdc) | STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX | Descriptor: | DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3'), PROTEIN (TRANSCRIPTION FACTOR) | Authors: | Jin, C, Marsden, I, Chen, X, Liao, X. | Deposit date: | 1999-05-05 | Release date: | 1999-07-05 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex. J.Mol.Biol., 289, 1999
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5GXJ
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![BU of 5gxj by Molmil](/molmil-images/mine/5gxj) | Zika Virus NS2B-NS3 protease | Descriptor: | FLAVIVIRUS_NS2B,LINKER,Peptidase S7 | Authors: | Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K. | Deposit date: | 2016-09-18 | Release date: | 2017-05-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Viral protease activation mechanism To Be Published
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5H6X
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![BU of 5h6x by Molmil](/molmil-images/mine/5h6x) | The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila | Descriptor: | GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION | Authors: | Zhang, N, Chen, X, Gong, X, Ge, H. | Deposit date: | 2016-11-15 | Release date: | 2017-11-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila Crystals, 8, 2018
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6DQF
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![BU of 6dqf by Molmil](/molmil-images/mine/6dqf) | |
6DQC
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![BU of 6dqc by Molmil](/molmil-images/mine/6dqc) | |
6DQ7
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![BU of 6dq7 by Molmil](/molmil-images/mine/6dq7) | |
4MQW
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![BU of 4mqw by Molmil](/molmil-images/mine/4mqw) | Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ... | Authors: | Jiang, X, Liu, H, Chen, X, He, X. | Deposit date: | 2013-09-16 | Release date: | 2014-04-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer. J.Biol.Chem., 289, 2014
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3V78
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![BU of 3v78 by Molmil](/molmil-images/mine/3v78) | Crystal Structure of Transcriptional Regulator | Descriptor: | ETHIDIUM, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) | Authors: | Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. | Deposit date: | 2011-12-20 | Release date: | 2012-12-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res., 40, 2012
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4D8P
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![BU of 4d8p by Molmil](/molmil-images/mine/4d8p) | Structural and functional studies of the trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) molecule | Descriptor: | GLYCEROL, HLA-DQA1 protein, Peptide from Gamma-gliadin,HLA class II histocompatibility antigen, ... | Authors: | Kim, C.-Y, Hotta, K, Mathews, I.I, Chen, X. | Deposit date: | 2012-01-11 | Release date: | 2012-03-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule J.Biol.Chem., 287, 2012
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4GQH
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![BU of 4gqh by Molmil](/molmil-images/mine/4gqh) | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies | Descriptor: | Capsid protein | Authors: | Li, X.Y, Song, B.A, Hu, D.Y, Chen, X, Wang, Z.C, Zeng, M.J, Yu, D.D, Chen, Z, Jin, L.H, Yang, S. | Deposit date: | 2012-08-23 | Release date: | 2013-08-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies To be Published
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3V6G
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![BU of 3v6g by Molmil](/molmil-images/mine/3v6g) | Crystal Structure of Transcriptional Regulator | Descriptor: | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) | Authors: | Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. | Deposit date: | 2011-12-19 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.821 Å) | Cite: | Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res., 40, 2012
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7YHN
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![BU of 7yhn by Molmil](/molmil-images/mine/7yhn) | ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X. | Deposit date: | 2022-07-14 | Release date: | 2023-07-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J.Med.Chem., 65, 2022
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6U8Q
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![BU of 6u8q by Molmil](/molmil-images/mine/6u8q) | CryoEM structure of HIV-1 cleaved synaptic complex (CSC) intasome | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | Authors: | Li, M, Chen, X, Craigie, R. | Deposit date: | 2019-09-05 | Release date: | 2020-02-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.67 Å) | Cite: | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
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7YCK
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![BU of 7yck by Molmil](/molmil-images/mine/7yck) | Crystal structure of SARS-CoV-2 Spike RBD in complex with FP-12A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FP-12A Fab heavy chain, FP-12A Fab light chain, ... | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-07-01 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
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7YCL
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![BU of 7ycl by Molmil](/molmil-images/mine/7ycl) | Crystal structure of SARS-CoV-2 Spike RBD in complex with IS-9A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IS-9A Fab heavy chain, IS-9A Fab light chain, ... | Authors: | Mohapatra, A, Chen, X. | Deposit date: | 2022-07-01 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
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7YCN
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![BU of 7ycn by Molmil](/molmil-images/mine/7ycn) | |
7SH1
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![BU of 7sh1 by Molmil](/molmil-images/mine/7sh1) | Class II UvrA protein - Ecm16 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Excinuclease ABC subunit UvrA, ... | Authors: | Grade, P, Erlandson, A, Ullah, A, Mathews, I.I, Chen, X, Kim, C.-Y, Mera, P.E. | Deposit date: | 2021-10-07 | Release date: | 2022-10-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi. Sci Rep, 13, 2023
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6VDK
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![BU of 6vdk by Molmil](/molmil-images/mine/6vdk) | CryoEM structure of HIV-1 conserved Intasome Core | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | Authors: | Li, M, Chen, X, Craigie, R. | Deposit date: | 2019-12-27 | Release date: | 2020-02-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
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7SGL
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![BU of 7sgl by Molmil](/molmil-images/mine/7sgl) | DNA-PK complex of DNA end processing | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | Authors: | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | Deposit date: | 2021-10-06 | Release date: | 2022-01-12 | Last modified: | 2022-01-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82, 2022
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1MOZ
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![BU of 1moz by Molmil](/molmil-images/mine/1moz) | ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae | Descriptor: | ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE | Authors: | Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A. | Deposit date: | 2002-09-10 | Release date: | 2002-10-09 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structures of Yeast ARF2 and ARL1:
DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE
AND FUNCTION OF ARF FAMILY GTPases J.Biol.Chem., 276, 2001
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6ML6
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![BU of 6ml6 by Molmil](/molmil-images/mine/6ml6) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpA 5mC Modification) | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*(5CM)P*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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6ML5
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![BU of 6ml5 by Molmil](/molmil-images/mine/6ml5) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4) | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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6ML4
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![BU of 6ml4 by Molmil](/molmil-images/mine/6ml4) | BTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 3) | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.482 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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6ML7
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![BU of 6ml7 by Molmil](/molmil-images/mine/6ml7) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpG 5mC Modification) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*(5CM)P*GP*AP*AP*TP*T)-3'), ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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