6U8Q

CryoEM structure of HIV-1 cleaved synaptic complex (CSC) intasome

Summary for 6U8Q

• Entry DOI: 10.2210/pdb6u8q/pdb
• EMDB information: 20689
• Descriptor: Integrase, DNA (27-MER), DNA (25-MER), ... (5 entities in total)
• Functional Keywords: site-specific recombination, retrovirus, integrase, integration, nucleoprotein complex, transferase-transferase inhibitor-dna complex, transferase/transferase inhibitor/dna
• Biological source: Human immunodeficiency virus 1 (HIV-1); More
• Total number of polymer chains: 16
• Total formula weight: 511638.83

Authors

Li, M.,Chen, X.,Craigie, R. (deposition date: 2019-09-05, release date: 2020-02-05, Last modification date: 2024-03-20)

• Primary citation: Li, M.,Chen, X.,Wang, H.,Jurado, K.A.,Engelman, A.N.,Craigie, R.; A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies.; J.Mol.Biol., 432:2055-2066, 2020; PubMed: 32061936; DOI: 10.1016/j.jmb.2020.01.040

Experimental method

ELECTRON MICROSCOPY (4.67 Å)