4EXP
| Structure of mouse Interleukin-34 in complex with mouse FMS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | Deposit date: | 2012-04-30 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim.Biophys.Acta, 1824, 2012
|
|
4EXN
| Crystal structure of mouse Interleukin-34 | Descriptor: | Interleukin-34, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | Deposit date: | 2012-04-30 | Release date: | 2012-05-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim.Biophys.Acta, 1824, 2012
|
|
5WWM
| Crystal structure of the TPR domain of Rrp5 | Descriptor: | SULFATE ION, rRNA biogenesis protein RRP5 | Authors: | Ye, K, Chen, X. | Deposit date: | 2017-01-03 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.809 Å) | Cite: | Correction: Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
|
|
6L03
| structure of PTP-MEG2 and MUNC18-1-pY145 peptide complex | Descriptor: | Tyrosine-protein phosphatase non-receptor type 9, stxbp1-pY145 peptide | Authors: | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | Deposit date: | 2019-09-25 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.084 Å) | Cite: | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
|
|
6KZQ
| structure of PTP-MEG2 and NSF-pY83 peptide complex | Descriptor: | NSF-pY83 peptide, Tyrosine-protein phosphatase non-receptor type 9 | Authors: | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | Deposit date: | 2019-09-25 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
|
|
5KOC
| Pavine N-methyltransferase in complex with S-adenosylmethionine pH 7 | Descriptor: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | Authors: | Torres, M.A, Hoffarth, E, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2016-06-30 | Release date: | 2016-09-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KOK
| Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25 | Descriptor: | (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, Pavine N-methyltransferase, ... | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2016-06-30 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KPC
| Pavine N-methyltransferase H206A mutant in complex with S-adenosylmethionine pH 6 | Descriptor: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2016-07-03 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KN4
| Pavine N-methyltransferase apoenzyme pH 6.0 | Descriptor: | Pavine N-methyltransferase | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2016-06-27 | Release date: | 2016-09-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KPG
| Pavine N-methyltransferase in complex with S-adenosylhomocysteine pH 7 | Descriptor: | Pavine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2016-07-04 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
7SGL
| DNA-PK complex of DNA end processing | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | Authors: | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | Deposit date: | 2021-10-06 | Release date: | 2022-01-12 | Last modified: | 2022-01-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82, 2022
|
|
3G5C
| Structural and biochemical studies on the ectodomain of human ADAM22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION | Authors: | Liu, H, Shim, A, Chen, X, He, X. | Deposit date: | 2009-02-04 | Release date: | 2009-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural and biochemical studies on the ectodomain of human ADAM22 J.Biol.Chem., 2009
|
|
1IK1
| Solution Structure of an RNA Hairpin from HRV-14 | Descriptor: | 5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3' | Authors: | Huang, H, Alexandrov, A, Chen, X, Barnes III, T.W, Zhang, H, Dutta, K, Pascal, S.M. | Deposit date: | 2001-05-01 | Release date: | 2001-07-18 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of an RNA hairpin from HRV-14. Biochemistry, 40, 2001
|
|
1MI8
| 2.0 Angstrom crystal structure of a DnaB intein from Synechocystis sp. PCC 6803 | Descriptor: | DnaB intein | Authors: | Ding, Y, Chen, X, Ferrandon, S, Xu, M, Rao, Z. | Deposit date: | 2002-08-22 | Release date: | 2003-08-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing J.Biol.Chem., 278, 2003
|
|
1QET
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | Descriptor: | RNA (5'-R(*GP*GP*AP*UP*GP*UP*CP*C)-3') | Authors: | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | Deposit date: | 1997-03-04 | Release date: | 1997-06-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
|
|
1QES
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | Descriptor: | RNA (5'-R(*GP*GP*AP*GP*UP*UP*CP*C)-3') | Authors: | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | Deposit date: | 1997-03-04 | Release date: | 1997-06-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
|
|
1R1V
| Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the Zn2-form | Descriptor: | ZINC ION, repressor protein | Authors: | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | Deposit date: | 2003-09-25 | Release date: | 2004-05-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R22
| Crystal structure of the cyanobacterial metallothionein repressor SmtB (C14S/C61S/C121S mutant) in the Zn2alpha5-form | Descriptor: | Transcriptional repressor smtB, ZINC ION | Authors: | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | Deposit date: | 2003-09-25 | Release date: | 2004-05-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R1U
| Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the apo-form | Descriptor: | repressor protein | Authors: | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | Deposit date: | 2003-09-25 | Release date: | 2004-05-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R23
| Crystal structure of the cyanobacterial metallothionein repressor SmtB in the Zn1-form (one Zn(II) per dimer) | Descriptor: | Transcriptional repressor smtB, ZINC ION | Authors: | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | Deposit date: | 2003-09-25 | Release date: | 2004-05-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
5ESW
| Crystal structure of Apo hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila | Descriptor: | PHOSPHATE ION, Purine/pyrimidine phosphoribosyltransferase | Authors: | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | Deposit date: | 2015-11-17 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis J.Struct.Biol., 194, 2016
|
|
5ESX
| Crystal structure of hypoxanthine-guanine phosphoribosyltransferase complexed with GMP from Legionella pneumophila | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Purine/pyrimidine phosphoribosyltransferase | Authors: | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | Deposit date: | 2015-11-17 | Release date: | 2016-03-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis J.Struct.Biol., 194, 2016
|
|
5X07
| Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site | Descriptor: | DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta | Authors: | Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y. | Deposit date: | 2017-01-20 | Release date: | 2017-08-16 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site Biochemistry, 56, 2017
|
|
2HDC
| STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX | Descriptor: | DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3'), PROTEIN (TRANSCRIPTION FACTOR) | Authors: | Jin, C, Marsden, I, Chen, X, Liao, X. | Deposit date: | 1999-05-05 | Release date: | 1999-07-05 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex. J.Mol.Biol., 289, 1999
|
|
1R1T
| Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form | Descriptor: | Transcriptional repressor smtB | Authors: | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | Deposit date: | 2003-09-25 | Release date: | 2004-05-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|