7N5V

ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20)

Summary for 7N5V

Entry DOI	10.2210/pdb7n5v/pdb
Descriptor	Zinc finger and BTB domain-containing protein 7A, DNA Strand I, DNA Strand II, ... (5 entities in total)
Functional Keywords	zinc-finger domain, gene expression, dna binding protein-dna complex, dna binding protein/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	9
Total formula weight	79827.99
Authors	Horton, J.R.,Ren, R.,Cheng, X. (deposition date: 2021-06-06, release date: 2022-06-08, Last modification date: 2023-10-25)
Primary citation	Ren, R.,Horton, J.R.,Chen, Q.,Yang, J.,Liu, B.,Huang, Y.,Blumenthal, R.M.,Zhang, X.,Cheng, X. Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia. J.Biol.Chem., 299:102885-102885, 2023 Cited by PubMed: 36626981 DOI: 10.1016/j.jbc.2023.102885 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.08 Å)

Structure validation