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6XYO
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Multiple system atrophy Type I alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYP
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Multiple system atrophy Type II-1 alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYQ
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Multiple system atrophy Type II-2 alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
8R1A
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Model of the membrane-bound GBP1 oligomer
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate binding protein 1, ...
著者Weismehl, M, Chu, X, Kutsch, M, Lauterjung, P, Herrmann, C, Kudryashev, M, Daumke, O.
登録日2023-11-01
公開日2024-01-17
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (26.799999 Å)
主引用文献Structural insights into the activation mechanism of antimicrobial GBP1.
Embo J., 43, 2024
9GG1
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P301T type I tau filaments from human brain
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2024-08-12
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献Novel tau filament folds in individuals with MAPT mutations P301L and P301T.
Biorxiv, 2024
9GG6
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P301T type II tau filaments from human brain
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2024-08-13
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Novel tau filament folds in individuals with MAPT mutations P301L and P301T.
Biorxiv, 2024
9GG0
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P301L tau filaments from human brain
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2024-08-12
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Novel tau filament folds in individuals with MAPT mutations P301L and P301T.
Biorxiv, 2024
8Q92
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P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line
分子名称: Microtubule-associated protein tau
著者Schweighauser, M, Murzin, A.G, Macdonald, J, Lavenir, I, Crowther, R.A, Scheres, S.H.W, Goedert, M.
登録日2023-08-19
公開日2023-10-11
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Acta Neuropathol Commun, 11, 2023
8Q96
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P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line
分子名称: Isoform Tau-E of Microtubule-associated protein tau, Unknown protein
著者Schweighauser, M, Murzin, A.G, Macdonald, J, Lavenir, I, Crowther, R.A, Scheres, S.H.W, Goedert, M.
登録日2023-08-19
公開日2023-10-11
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Acta Neuropathol Commun, 11, 2023
1BZG
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BU of 1bzg by Molmil
THE SOLUTION STRUCTURE OF HUMAN PARATHYROID HORMONE-RELATED PROTEIN (1-34) IN NEAR-PHYSIOLOGICAL SOLUTION, NMR, 30 STRUCTURES
分子名称: PARATHYROID HORMONE-RELATED PROTEIN
著者Weidler, M, Marx, U.C, Seidel, G, Roesch, P.
登録日1998-10-28
公開日1999-05-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of human parathyroid hormone-related protein(1-34) in near-physiological solution.
FEBS Lett., 444, 1999
4BTS
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BU of 4bts by Molmil
THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A
分子名称: 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN RACK1, 40S RIBOSOMAL PROTEIN RPS10E, ...
著者Weisser, M, Voigts-Hoffmann, F, Rabl, J, Leibundgut, M, Ban, N.
登録日2013-06-19
公開日2013-07-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.703 Å)
主引用文献The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Nat. Struct. Mol. Biol., 20, 2013
8P34
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Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
分子名称: Microtubule-associated protein tau
著者Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L.
登録日2023-05-17
公開日2023-07-05
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol, 146, 2023
1P23
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BU of 1p23 by Molmil
STRUCTURE OF THE DIMERIZED CYTOPLASMIC DOMAIN OF P23 IN SOLUTION, NMR, 10 STRUCTURES
分子名称: TRANSMEMBRANE PROTEIN TMP21 PRECURSOR
著者Weidler, M, Reinhard, C, Wieland, F.T, Roesch, P.
登録日1998-11-17
公開日2000-06-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structure of the cytoplasmic domain of p23 in solution: implications for the formation of COPI vesicles.
Biochem.Biophys.Res.Commun., 271, 2000
5OA9
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Human translation re-initiation complex containing eIF2D
分子名称: Eukaryotic translation initiation factor 2D
著者Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N.
登録日2017-06-21
公開日2017-07-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Functional Insights into Human Re-initiation Complexes.
Mol. Cell, 67, 2017
5OA3
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Human 40S-eIF2D-re-initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N.
登録日2017-06-20
公開日2017-08-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural and Functional Insights into Human Re-initiation Complexes.
Mol. Cell, 67, 2017
2LNY
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BU of 2lny by Molmil
ShB peptide structure bound to negatively charged lipid-bilayer after Molecular Dynamics refinement
分子名称: ShB peptide
著者Weingarth, M.
登録日2012-01-06
公開日2012-08-08
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Supramolecular structure of membrane-associated polypeptides by combining solid-state NMR and molecular dynamics simulations.
Biophys.J., 103, 2012
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
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TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWM
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TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
1QIF
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT C) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
分子名称: ACETYLCHOLINESTERASE
著者Kryger, G, Weik, M, Ravelli, R.B.G.
登録日1999-06-14
公開日2000-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QII
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT F) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
分子名称: ACETYLCHOLINESTERASE
著者Kryger, G, Weik, M, Ravelli, R.B.G.
登録日1999-06-14
公開日2000-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIE
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT B) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
分子名称: ACETYLCHOLINESTERASE
著者Kryger, G, Weik, M, Ravelli, R.B.G.
登録日1999-06-14
公開日2000-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIH
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT E) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
分子名称: PROTEIN (ACETYLCHOLINESTERASE)
著者Kryger, G, Weik, M, Ravelli, R.B.G.
登録日1999-06-14
公開日2000-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000

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