4BTS

THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A

Summary for 4BTS

Entry DOI	10.2210/pdb4bts/pdb
Descriptor	TRANSLATION INITIATION FACTOR EIF-1A FAMILY PROTEIN, 40S RIBOSOMAL PROTEIN RPS31E, 18S ribosomal RNA, ... (39 entities in total)
Functional Keywords	ribosome, translation, translation initiation, small ribosomal subunit, 40s, eif1a, eif1, translation initiation factor, eukaryotic translation initiation
Biological source	Tetrahymena thermophila SB210 More
Cellular location	Cytoplasm : E6PBR9 E6PBR8
Total number of polymer chains	144
Total formula weight	4947943.00
Authors	Weisser, M.,Voigts-Hoffmann, F.,Rabl, J.,Leibundgut, M.,Ban, N. (deposition date: 2013-06-19, release date: 2013-07-17, Last modification date: 2023-12-20)
Primary citation	Weisser, M.,Voigts-Hoffmann, F.,Rabl, J.,Leibundgut, M.,Ban, N. The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A. Nat. Struct. Mol. Biol., 20:1015-1017, 2013 Cited by PubMed Abstract: Eukaryotic translation initiation factors (eIFs) 1A and 1 are central players in the complex process of start-codon recognition. To improve mechanistic understanding of this process, we determined the crystal structure of the 40S ribosomal subunit in complex with eIF1A and eIF1 from Tetrahymena thermophila at a resolution of 3.7 Å. It reveals the positions of the two factors on the 40S and the conformational changes that accompany their binding. PubMed: 23851459 DOI: 10.1038/nsmb.2622 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.703 Å)

Structure validation