1OS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1os1 by Molmil](/molmil-images/mine/1os1) | Structure of Phosphoenolpyruvate Carboxykinase complexed with ATP,Mg, Ca and pyruvate. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Sudom, A, Walters, R, Pastushok, L, Goldie, D, Prasad, L, Delbaere, L.T, Goldie, H. | 登録日 | 2003-03-18 | 公開日 | 2003-09-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanisms of activation of phosphoenolpyruvate carboxykinase from Escherichia coli by Ca2+ and of desensitization by trypsin. J.BACTERIOL., 185, 2003
|
|
8FTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ftg by Molmil](/molmil-images/mine/8ftg) | Biophysical and Structural Characterization of an Anti-Caffeine VHH Antibody | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-Caffeine VHH Antibody, CAFFEINE, ... | 著者 | Horn, J.R, Smith, C.A, Sonneson, G.J, Walter, R. | 登録日 | 2023-01-12 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Molecular recognition requires dimerization of a VHH antibody. Mabs, 15, 2023
|
|
2HC1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hc1 by Molmil](/molmil-images/mine/2hc1) | Engineered catalytic domain of protein tyrosine phosphatase HPTPbeta. | 分子名称: | ACETATE ION, CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta | 著者 | Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M. | 登録日 | 2006-06-14 | 公開日 | 2006-06-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2HC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hc2 by Molmil](/molmil-images/mine/2hc2) | Engineered protein tyrosine phosphatase beta catalytic domain | 分子名称: | MAGNESIUM ION, Receptor-type tyrosine-protein phosphatase beta, SODIUM ION | 著者 | Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M. | 登録日 | 2006-06-15 | 公開日 | 2006-06-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
4POU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pou by Molmil](/molmil-images/mine/4pou) | VHH-metal in Complex with RNase A | 分子名称: | Ribonuclease pancreatic, VHH Antibody | 著者 | Fanning, S.W, Walter, R, Horn, J.R. | 登録日 | 2014-02-26 | 公開日 | 2014-09-24 | 最終更新日 | 2014-10-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site. Protein Eng.Des.Sel., 27, 2014
|
|
4POY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4poy by Molmil](/molmil-images/mine/4poy) | |
4PPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ppt by Molmil](/molmil-images/mine/4ppt) | |
1YGE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yge by Molmil](/molmil-images/mine/1yge) | LIPOXYGENASE-1 (SOYBEAN) AT 100K | 分子名称: | FE (III) ION, LIPOXYGENASE-1 | 著者 | Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B. | 登録日 | 1996-06-04 | 公開日 | 1997-07-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution. Biochemistry, 35, 1996
|
|
4XI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xi3 by Molmil](/molmil-images/mine/4xi3) | Estrogen Receptor Alpha Ligand Binding Domain in Complex with Bazedoxifene | 分子名称: | Bazedoxifene, Estrogen receptor | 著者 | Fanning, S.W, Mayne, C.G, Toy, W, Carlson, K, Greene, B, Nowak, J, Walter, R, Panchamukhi, S, Tajhorshid, E, Nettles, K.W, Chandarlapaty, S, Katzenellenbogen, J, Greene, G.L. | 登録日 | 2015-01-06 | 公開日 | 2016-01-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | 主引用文献 | The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife, 7, 2018
|
|
2I3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i3u by Molmil](/molmil-images/mine/2i3u) | Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors | 分子名称: | Receptor-type tyrosine-protein phosphatase beta | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | 登録日 | 2006-08-20 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2I4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i4e by Molmil](/molmil-images/mine/2i4e) | Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors | 分子名称: | Receptor-type tyrosine-protein phosphatase beta, VANADATE ION | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | 登録日 | 2006-08-21 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2I3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i3r by Molmil](/molmil-images/mine/2i3r) | Engineered catalytic domain of protein tyrosine phosphatase HPTPbeta | 分子名称: | CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | 登録日 | 2006-08-20 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2I4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i4g by Molmil](/molmil-images/mine/2i4g) | Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with a sulfamic acid (soaking experiment) | 分子名称: | CHLORIDE ION, N-(TERT-BUTOXYCARBONYL)-L-TYROSYL-N-METHYL-4-(SULFOAMINO)-L-PHENYLALANINAMIDE, Receptor-type tyrosine-protein phosphatase beta | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | 登録日 | 2006-08-21 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2I5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i5x by Molmil](/molmil-images/mine/2i5x) | Engineering the PTPbeta catalytic domain with improved crystallization properties | 分子名称: | (4-ETHYLPHENYL)SULFAMIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Klopfenstein, S. | 登録日 | 2006-08-26 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2I4H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i4h by Molmil](/molmil-images/mine/2i4h) | Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor | 分子名称: | CHLORIDE ION, MAGNESIUM ION, N-(TERT-BUTOXYCARBONYL)-L-TYROSYL-N-METHYL-4-(SULFOAMINO)-L-PHENYLALANINAMIDE, ... | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | 登録日 | 2006-08-21 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2HFP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hfp by Molmil](/molmil-images/mine/2hfp) | Crystal Structure of PPAR Gamma with N-sulfonyl-2-indole carboxamide ligands | 分子名称: | 3-(4-METHOXYPHENYL)-N-(PHENYLSULFONYL)-1-[3-(TRIFLUOROMETHYL)BENZYL]-1H-INDOLE-2-CARBOXAMIDE, Peroxisome proliferator-activated receptor gamma, SRC Peptide Fragment | 著者 | Pokross, M.E, Evdokimov, A.G, Walter, R.L, Mekel, M.J, Hopkins, C.R. | 登録日 | 2006-06-25 | 公開日 | 2006-09-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis. Bioorg.Med.Chem.Lett., 16, 2006
|
|
2RHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rhs by Molmil](/molmil-images/mine/2rhs) | |
2RHQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rhq by Molmil](/molmil-images/mine/2rhq) | |
3D9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d9a by Molmil](/molmil-images/mine/3d9a) | High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme | 分子名称: | Heavy Chain of HyHel10 Antibody Fragment (Fab), Light Chain of HyHel10 Antibody Fragment (Fab), Lysozyme C | 著者 | DeSantis, M.E, Li, M, Shanmuganathan, A, Acchione, M, Walter, R, Wlodawer, A, Smith-Gill, S. | 登録日 | 2008-05-27 | 公開日 | 2008-06-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies. Mol.Immunol., 47, 2009
|
|
3PZW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pzw by Molmil](/molmil-images/mine/3pzw) | |
1F8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f8n by Molmil](/molmil-images/mine/1f8n) | |
1FGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fgt by Molmil](/molmil-images/mine/1fgt) | |
1FGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fgm by Molmil](/molmil-images/mine/1fgm) | |
1FGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fgq by Molmil](/molmil-images/mine/1fgq) | |
1FGR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fgr by Molmil](/molmil-images/mine/1fgr) | |