3D9A

High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme

Summary for 3D9A

• Entry DOI: 10.2210/pdb3d9a/pdb
• Related: 1NDM 3HFM
• Descriptor: Lysozyme C, Light Chain of HyHel10 Antibody Fragment (Fab), Heavy Chain of HyHel10 Antibody Fragment (Fab), ... (4 entities in total)
• Functional Keywords: lysozyme, hyhel10, fab, antibody, antigen, allergen, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 3
• Total formula weight: 60565.08

Authors

DeSantis, M.E.,Li, M.,Shanmuganathan, A.,Acchione, M.,Walter, R.,Wlodawer, A.,Smith-Gill, S. (deposition date: 2008-05-27, release date: 2008-06-10, Last modification date: 2023-08-30)

• Primary citation: Acchione, M.,Lipschultz, C.A.,DeSantis, M.E.,Shanmuganathan, A.,Li, M.,Wlodawer, A.,Tarasov, S.,Smith-Gill, S.J.; Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies.; Mol.Immunol., 47:457-464, 2009; PubMed: 19781789; DOI: 10.1016/j.molimm.2009.08.018

Experimental method

X-RAY DIFFRACTION (1.2 Å)