2N8H
 
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5UFX
 | | Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1074 | | Descriptor: | (2S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3R)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-1-benzopyran-7-ol, Estrogen receptor | | Authors: | Fanning, S.W, Hodges-Gallagher, L, Myles, D.C, Sun, R, Fowler, C.E, Green, B.D, Harmon, C.L, Greene, G.L, Kushner, P.J. | | Deposit date: | 2017-01-06 | | Release date: | 2018-01-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5503 Å) | | Cite: | Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.
Nat Commun, 9, 2018
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5UFW
 | | Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1154 | | Descriptor: | (2S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3S)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-1-benzopyran-7-ol, Estrogen receptor | | Authors: | Fanning, S.W, Hodges-Gallagher, L, Myles, D.C, Sun, R, Fowler, C.E, Green, B.D, Harmon, C.L, Greene, G.L, Kushner, P.J. | | Deposit date: | 2017-01-06 | | Release date: | 2018-01-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.583 Å) | | Cite: | Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.
Nat Commun, 9, 2018
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6C42
 | | Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1156 | | Descriptor: | (2R,3S,4R)-3-(4-hydroxyphenyl)-4-methyl-2-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-3,4-dihydro-2H-1-benzopyran-7-ol, Estrogen receptor | | Authors: | Fanning, S.W, Hodges-Gallager, L, Myles, D.C, Sun, R, Fowler, C.E, Green, B.D, Harmon, C.L, Greene, G.L, Kushner, P.J. | | Deposit date: | 2018-01-11 | | Release date: | 2018-02-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.
Nat Commun, 9, 2018
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4XI3
 | | Estrogen Receptor Alpha Ligand Binding Domain in Complex with Bazedoxifene | | Descriptor: | Bazedoxifene, Estrogen receptor | | Authors: | Fanning, S.W, Mayne, C.G, Toy, W, Carlson, K, Greene, B, Nowak, J, Walter, R, Panchamukhi, S, Tajhorshid, E, Nettles, K.W, Chandarlapaty, S, Katzenellenbogen, J, Greene, G.L. | | Deposit date: | 2015-01-06 | | Release date: | 2016-01-13 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.491 Å) | | Cite: | The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Elife, 7, 2018
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7LIX
 | | CaRSP1 and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum | | Descriptor: | B-phycoerythrin beta chain, CaRSP1, PHYCOERYTHROBILIN | | Authors: | Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G. | | Deposit date: | 2021-01-28 | | Release date: | 2021-04-07 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
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7LIY
 | | CaRSP2 and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum | | Descriptor: | B-phycoerythrin beta chain, CaRSP2, PHYCOERYTHROBILIN | | Authors: | Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G. | | Deposit date: | 2021-01-28 | | Release date: | 2021-04-07 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
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7LIZ
 | | LR6 rod linker and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum | | Descriptor: | B-phycoerythrin beta chain, LR6, PHYCOERYTHROBILIN | | Authors: | Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G. | | Deposit date: | 2021-01-28 | | Release date: | 2021-04-07 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
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7LJ0
 | | Linker 3 and scaffolded phycoerythrin beta subunit from the phycobilisome of Porphyridium purpureum | | Descriptor: | B-phycoerythrin beta chain, Linker 3, PHYCOERYTHROBILIN | | Authors: | Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G. | | Deposit date: | 2021-01-28 | | Release date: | 2021-04-07 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
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1YHU
 | | Crystal structure of Riftia pachyptila C1 hemoglobin reveals novel assembly of 24 subunits. | | Descriptor: | Giant hemoglobins B chain, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Flores, J.F, Fisher, C.R, Carney, S.L, Green, B.N, Freytag, J.K, Schaeffer, S.W, Royer, W.E. | | Deposit date: | 2005-01-10 | | Release date: | 2005-02-08 | | Last modified: | 2013-03-06 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Sulfide binding is mediated by zinc ions discovered in the crystal structure of a hydrothermal vent tubeworm hemoglobin.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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