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4C3G
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BU of 4c3g by Molmil
cryo-EM structure of activated and oligomeric restriction endonuclease SgrAI
分子名称: 5'-D(*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*CP *CP*AP*CP*GP*CP*AP*TP*CP)-3', 5'-D(*GP*AP*TP*GP*CP*GP*TP*GP*GP*GP*TP*CP*TP*TP *CP*AP*CP*AP)-3', SGRAIR RESTRICTION ENZYME
著者Lyumkis, D, Talley, H, Stewart, A, Shah, S, Park, C.K, Tama, F, Potter, C.S, Carragher, B, Horton, N.C.
登録日2013-08-23
公開日2013-09-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Allosteric Regulation of DNA Cleavage and Sequence-Specificity Through Run-on Oligomerization.
Structure, 21, 2013
6K8Q
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BU of 6k8q by Molmil
Solution structure of the intermembrane space domain of the mitochondrial import protein Tim21 from S. cerevisiae
分子名称: Mitochondrial import inner membrane translocase subunit TIM21
著者Bala, S, Shinya, S, Srivastava, A, Shimada, A, Kobayashi, N, Kojima, C, Tama, F, Miyashita, O, Kohda, D.
登録日2019-06-13
公開日2019-09-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Crystal contact-free conformation of an intrinsically flexible loop in protein crystal: Tim21 as the case study.
Biochim Biophys Acta Gen Subj, 1864, 2020
3J04
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BU of 3j04 by Molmil
EM structure of the heavy meromyosin subfragment of Chick smooth muscle Myosin with regulatory light chain in phosphorylated state
分子名称: Myosin light polypeptide 6, Myosin regulatory light chain 2, smooth muscle major isoform, ...
著者Baumann, B.A.J, Taylor, D, Huang, Z, Tama, F, Fagnant, P.M, Trybus, K, Taylor, K.
登録日2011-02-18
公開日2011-11-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation.
J.Mol.Biol., 415, 2012
2AKH
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BU of 2akh by Molmil
Normal mode-based flexible fitted coordinates of a non-translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli
分子名称: Preprotein translocase secE subunit, Preprotein translocase secY subunit, Protein-export membrane protein secG
著者Mitra, K.M, Schaffitzel, C, Shaikh, T, Tama, F, Jenni, S, Brooks III, C.L, Ban, N, Frank, J.
登録日2005-08-03
公開日2005-11-15
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (14.9 Å)
主引用文献Structure of the E. coli protein-conducting channel bound to a translating ribosome.
Nature, 438, 2005
2AKI
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BU of 2aki by Molmil
Normal mode-based flexible fitted coordinates of a translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli
分子名称: Preprotein translocase secE subunit, Preprotein translocase secY subunit, Protein-export membrane protein secG
著者Mitra, K, Schaffitzel, C, Shaikh, T, Tama, F, Jenni, S, Brooks III, C.L, Ban, N, Frank, J.
登録日2005-08-03
公開日2005-11-15
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (14.9 Å)
主引用文献Structure of the E. coli protein-conducting channel bound to a translating ribosome.
Nature, 438, 2005
1R4D
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BU of 1r4d by Molmil
Solution structure of the chimeric L/D DNA oligonucleotide d(C8metGCGC(L)G(L)CGCG)2
分子名称: 5'-D(*CP*(8MG)P*CP*GP*(0DC)P*(0DG)P*CP*GP*CP*G)-3'
著者Cherrak, I, Mauffret, O, Santamaria, F, Rayner, B, Hocquet, A, Ghomi, M, Fermandjian, S.
登録日2003-10-06
公開日2003-10-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献L-nucleotides and 8-methylguanine of d(C1m8G2C3G4C5LG6LC7G8C9G10)2 act cooperatively to promote a left-handed helix under physiological salt conditions.
Nucleic Acids Res., 31, 2003
1FV8
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BU of 1fv8 by Molmil
NMR STUDY OF AN HETEROCHIRAL HAIRPIN
分子名称: 5'-D(*TP*AP*TP*CP*AP*(0DT)P*CP*GP*AP*TP*A)-3'
著者El Amri, C, Mauffret, O, Santamaria, F, Rayner, B, Fermandjian, S.
登録日2000-09-19
公開日2000-10-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR study of a heterochiral DNA hairpin:impact of L-enantiomery in the loop.
J.Biomol.Struct.Dyn., 19, 2001
1FV7
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BU of 1fv7 by Molmil
A TWO B-Z JUNCTION CONTAINING DNA RESOLVES INTO AN ALL RIGHT HANDED DOUBLE HELIX
分子名称: 5'-D(*(5CM)P*GP*(5CM)P*GP*(0DC)P*(0DG)P*(5CM)P*GP*(5CM)P*G)-3'
著者Mauffret, O, El Amri, C, Santamaria, F, Tevanian, G, Rayner, B, Fermandjian, S.
登録日2000-09-19
公開日2000-10-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A two B-Z junction containing DNA resolves into an all right-handed double-helix.
Nucleic Acids Res., 28, 2000
4V4W
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BU of 4v4w by Molmil
Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
著者Mitra, K, Frank, J.
登録日2006-05-09
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4V4V
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BU of 4v4v by Molmil
Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
著者Mitra, K, Frank, J.
登録日2006-05-09
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
6OF7
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BU of 6of7 by Molmil
Crystal structure of the CRY1-PER2 complex
分子名称: Cryptochrome-1, Period circadian protein homolog 2
著者Michael, A.K, Fribourgh, J.L, Tripathi, S.M, Partch, C.L.
登録日2019-03-28
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.
Elife, 9, 2020
6DTL
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BU of 6dtl by Molmil
Mitogen-activated protein kinase 6
分子名称: Mitogen-activated protein kinase 6
著者Ruble, J.
登録日2018-06-17
公開日2019-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP kinases to SPEECHLESS.
Nat.Plants, 5, 2019
7V8Y
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BU of 7v8y by Molmil
Crystal structure of mouse CRY2 in complex with SHP1703 compound
分子名称: 1-[(2R)-3-[3,6-bis(fluoranyl)carbazol-9-yl]-2-oxidanyl-propyl]imidazolidin-2-one, Cryptochrome-2
著者Miller, S.A, Hirota, T.
登録日2021-08-23
公開日2022-08-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8Z
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BU of 7v8z by Molmil
Crystal structure of mouse CRY2 in complex with SHP656 compound
分子名称: 1-[(2R)-3-[3,6-bis(fluoranyl)carbazol-9-yl]-2-oxidanyl-propyl]imidazolidin-2-one, Cryptochrome-2
著者Miller, S.A, Hirota, T.
登録日2021-08-23
公開日2022-08-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WSV
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BU of 7wsv by Molmil
Cryo-EM structure of the N-terminal deletion mutant of human pannexin-1 in a nanodisc
分子名称: Pannexin-1
著者Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A.
登録日2022-02-01
公開日2022-02-16
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
6A1C
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BU of 6a1c by Molmil
Crystal structure of the CK2a1-go289 complex
分子名称: 1,2-ETHANEDIOL, 5-bromanyl-2-methoxy-4-[(E)-(3-methylsulfanyl-5-phenyl-1,2,4-triazol-4-yl)iminomethyl]phenol, Casein kinase II subunit alpha, ...
著者Kinoshita, T, Tsuyuguchi, M.
登録日2018-06-07
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
Sci Adv, 5, 2019
6K7F
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BU of 6k7f by Molmil
Crystal structure of MBPholo-Tim21 fusion protein with a 17-residue helical linker
分子名称: Maltose/maltodextrin-binding periplasmic protein,Mitochondrial import inner membrane translocase subunit TIM21, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Bala, S, Shimada, A, Kohda, D.
登録日2019-06-07
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal contact-free conformation of an intrinsically flexible loop in protein crystal: Tim21 as the case study.
Biochim Biophys Acta Gen Subj, 1864, 2020
6K7D
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BU of 6k7d by Molmil
Crystal structure of MBPapo-Tim21 fusion protein with a 16-residue helical linker
分子名称: Maltose/maltodextrin-binding periplasmic protein,Mitochondrial import inner membrane translocase subunit TIM21
著者Bala, S, Shimada, A, Kohda, D.
登録日2019-06-07
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal contact-free conformation of an intrinsically flexible loop in protein crystal: Tim21 as the case study.
Biochim Biophys Acta Gen Subj, 1864, 2020
6K7E
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BU of 6k7e by Molmil
Crystal structure of MBPapo-Tim21 fusion protein with a 17-residue helical linker
分子名称: Maltose/maltodextrin-binding periplasmic protein,Mitochondrial import inner membrane translocase subunit TIM21
著者Bala, S, Shimada, A, Kohda, D.
登録日2019-06-07
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.534 Å)
主引用文献Crystal contact-free conformation of an intrinsically flexible loop in protein crystal: Tim21 as the case study.
Biochim Biophys Acta Gen Subj, 1864, 2020
6KX8
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BU of 6kx8 by Molmil
Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX7
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BU of 6kx7 by Molmil
Crystal structure of mouse Cryptochrome 1 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX5
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BU of 6kx5 by Molmil
Crystal structure of mouse Cryptochrome 1 in complex with KL044 compound
分子名称: 2-carbazol-9-yl-N-(2-chloranyl-6-cyano-phenyl)ethanamide, Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX4
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BU of 6kx4 by Molmil
Crystal structure of mouse Cryptochrome 1 apo form
分子名称: Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX6
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BU of 6kx6 by Molmil
Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound
分子名称: Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6LXV
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BU of 6lxv by Molmil
Cryo-EM structure of phosphoketolase from Bifidobacterium longum
分子名称: CALCIUM ION, Phosphoketolase, THIAMINE DIPHOSPHATE
著者Nakata, K, Miyazaki, N, Yamaguchi, H, Hirose, M, Miyano, H, Mizukoshi, T, Kashiwagi, T, Iwasaki, K.
登録日2020-02-12
公開日2021-02-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献High-resolution structure of phosphoketolase from Bifidobacterium longum determined by cryo-EM single-particle analysis.
J.Struct.Biol., 214, 2022

 

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