7DLI

Crystal structure of mouse CRY1 in complex with KL001 compound

Summary for 7DLI

Entry DOI	10.2210/pdb7dli/pdb
Descriptor	Cryptochrome-1, N-[(2R)-3-carbazol-9-yl-2-oxidanyl-propyl]-N-(furan-2-ylmethyl)methanesulfonamide, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	cry, cry1, cryptochrome, phr, circadian clock protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	3
Total formula weight	173372.69
Authors	Miller, S.A.,Aikawa, Y.,Hirota, T. (deposition date: 2020-11-27, release date: 2021-06-23, Last modification date: 2023-11-29)
Primary citation	Miller, S.,Srivastava, A.,Nagai, Y.,Aikawa, Y.,Tama, F.,Hirota, T. Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34172584 DOI: 10.1073/pnas.2026191118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation