7F8J
Cryo-EM structure of human pannexin-1 in a nanodisc
Summary for 7F8J
Entry DOI | 10.2210/pdb7f8j/pdb |
EMDB information | 31489 |
Descriptor | Pannexin-1, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (2 entities in total) |
Functional Keywords | atp release channel, vertebrate innexin homolog, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 7 |
Total formula weight | 368580.23 |
Authors | Kuzuya, M.,Hirano, H.,Hayashida, K.,Watanabe, M.,Kobayashi, K.,Tani, K.,Fujiyoshi, Y.,Oshima, A. (deposition date: 2021-07-02, release date: 2022-01-26, Last modification date: 2022-02-23) |
Primary citation | Kuzuya, M.,Hirano, H.,Hayashida, K.,Watanabe, M.,Kobayashi, K.,Terada, T.,Mahmood, M.I.,Tama, F.,Tani, K.,Fujiyoshi, Y.,Oshima, A. Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15:eabg6941-eabg6941, 2022 Cited by PubMed: 35133866DOI: 10.1126/scisignal.abg6941 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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