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BU of 4qf1 by Molmil

Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
分子名称:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
著者	Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日	2014-05-19
公開日	2015-02-18
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved. Immunity, 41, 2014

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BU of 5t4z by Molmil

STRUCTURE OF THE ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 WITH FREE MAN9 GLYCAN
分子名称:	CALCIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, antibody DH501 Fab heavy chain, ...
著者	Nicely, N.I, Haynes, B.F.
登録日	2016-08-30
公開日	2017-03-08
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.991 Å)
主引用文献	Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Rep, 18, 2017

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BU of 5iie by Molmil

STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3
分子名称:	antibody DH501 FabH chain, antibody DH501 light chain
著者	Nicely, N.I, Haynes, B.F.
登録日	2016-03-01
公開日	2017-03-01
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Rep, 18, 2017

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BU of 8dtk by Molmil

Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
著者	May, A.J, Manne, K, Acharya, P.
登録日	2022-07-25
公開日	2023-08-02
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.77 Å)
主引用文献	Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates. Biorxiv, 2023

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BU of 5f6i by Molmil

Crystal Structure of Tier 2 Neutralizing Antibody DH428 from a Rhesus Macaque
分子名称:	DH428 Antibody Heavy Chain, DH428 Antibody Light Chain
著者	Fera, D, Harrison, S.C.
登録日	2015-12-06
公開日	2016-01-13
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.32 Å)
主引用文献	Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016

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BU of 5f6h by Molmil

Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque
分子名称:	DH427 Antibody Heavy Chain, DH427 Antibody Light Chain
著者	Fera, D, Harrison, S.C.
登録日	2015-12-06
公開日	2016-01-13
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.66 Å)
主引用文献	Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016

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BU of 5f6j by Molmil

Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core
分子名称:	DH427 Antibody Heavy Chain, DH427 Antibody Light Chain, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C
著者	Fera, D, Harrison, S.C.
登録日	2015-12-06
公開日	2016-01-13
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (6.63 Å)
主引用文献	Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016

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BU of 7ld1 by Molmil

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-12
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

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BU of 7lcn by Molmil

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1050.1 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-11
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.35 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

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BU of 7lab by Molmil

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-06
公開日	2021-03-10
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.97 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

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BU of 7laa by Molmil

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1041 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-06
公開日	2021-03-17
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.42 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

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BU of 7ljr by Molmil

SARS-CoV-2 Spike Protein Trimer bound to DH1043 fab
分子名称:	Fab DH1043 heavy chain, Fab DH1043 light chain, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-01-30
公開日	2021-03-31
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (3.66 Å)
主引用文献	The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates. Biorxiv, 2021

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件を2024-06-26に公開中

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