7LJR

SARS-CoV-2 Spike Protein Trimer bound to DH1043 fab

Summary for 7LJR

• Entry DOI: 10.2210/pdb7ljr/pdb
• EMDB information: 23400
• Descriptor: Spike glycoprotein, Fab DH1043 heavy chain, Fab DH1043 light chain (3 entities in total)
• Functional Keywords: sars-cov-2 spike protein trimer, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 5
• Total formula weight: 504155.61

Authors

Gobeil, S.,Acharya, P. (deposition date: 2021-01-30, release date: 2021-03-31, Last modification date: 2024-03-06)

• Primary citation: Li, D.,Edwards, R.J.,Manne, K.,Martinez, D.R.,Schafer, A.,Alam, S.M.,Wiehe, K.,Lu, X.,Parks, R.,Sutherland, L.L.,Oguin, T.H.,McDanal, C.,Perez, L.G.,Mansouri, K.,Gobeil, S.M.C.,Janowska, K.,Stalls, V.,Kopp, M.,Cai, F.,Lee, E.,Foulger, A.,Hernandez, G.E.,Sanzone, A.,Tilahun, K.,Jiang, C.,Tse, L.V.,Bock, K.W.,Minai, M.,Nagata, B.M.,Cronin, K.,Gee-Lai, V.,Deyton, M.,Barr, M.,Von Holle, T.,Macintyre, A.N.,Stover, E.,Feldman, J.,Hauser, B.M.,Caradonna, T.M.,Scobey, T.D.,Moody, M.A.,Cain, D.W.,DeMarco, C.T.,Denny, T.N.,Woods, C.W.,Petzold, E.W.,Schmidt, A.G.,Teng, I.T.,Zhou, T.,Kwong, P.D.,Mascola, J.R.,Graham, B.S.,Moore, I.N.,Seder, R.,Andersen, H.,Lewis, M.G.,Montefiori, D.C.,Sempowski, G.D.,Baric, R.S.,Acharya, P.,Haynes, B.F.,Saunders, K.O.; The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates.; Biorxiv, 2021; PubMed: 33442694; DOI: 10.1101/2020.12.31.424729

Experimental method

ELECTRON MICROSCOPY (3.66 Å)