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5F7E
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BU of 5f7e by Molmil
Crystal structure of germ-line precursor of 3BNC60 Fab
分子名称: Fab heavy chain, Fab light chain
著者Sievers, S.A, Scharf, L, Jiang, S, Bjorkman, P.J.
登録日2015-12-08
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
4NIO
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BU of 4nio by Molmil
GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis
分子名称: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIP
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BU of 4nip by Molmil
GVIGIAQ segment 147-153 from Human Superoxide Dismutase
分子名称: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIN
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BU of 4nin by Molmil
DSVISLS segment 101-107 from Human Superoxide Dismutase
分子名称: DSVISLS segment from Superoxide dismutase [Cu-Zn], ZINC ION
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
5UEL
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BU of 5uel by Molmil
Crystal structure of 354NC102 Fab
分子名称: 354NC102 Fab Heavy Chain, 354NC102 Fab Light Chain, SULFATE ION
著者Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
登録日2017-01-02
公開日2017-02-01
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UEM
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BU of 5uem by Molmil
Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 354NC37 Fab Heavy Chain, ...
著者Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
登録日2017-01-02
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
6C4O
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BU of 6c4o by Molmil
AMYLOID FORMING PEPTIDE TIAALLS FROM TRANSTHYRETIN
分子名称: THR-ILE-ALA-ALA-LEU-LEU-SER
著者Sievers, S.A, Sawaya, M.R, Saelices, L, Eisenberg, D.S.
登録日2018-01-12
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3S
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BU of 6c3s by Molmil
AMYLOID FORMING PEPTIDE YTIAAL FROM TRANSTHYRETIN
分子名称: TYR-THR-ILE-ALA-ALA-LEU
著者Sievers, S.A, Sawaya, M.R, Saelices, L, Eisenberg, D.S.
登録日2018-01-10
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3T
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BU of 6c3t by Molmil
AMYLOID FORMING PEPTIDE AADTWE FROM TRANSTHYRETIN WITH ATTR-D38A MUTATION ASSOCIATED WITH A FAMILIAL FORM OF TRANSTHYRETIN AMYLOIDOSIS
分子名称: ALA-ALA-ASP-THR-TRP-GLU
著者Sievers, S.A, Sawaya, M.R, Saelices, L, Eisenberg, D.S.
登録日2018-01-10
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
3DG1
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BU of 3dg1 by Molmil
Segment SSTNVG derived from IAPP
分子名称: SSTNVG from Islet Amyloid Polypeptide
著者Wiltzius, J.J, Sievers, S.A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2008-06-12
公開日2008-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Protein Sci., 17, 2008
3DGJ
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BU of 3dgj by Molmil
NNFGAIL segment from Islet Amyloid Polypeptide (IAPP or amylin)
分子名称: NNFGAIL peptide
著者Wiltzius, J.J, Sievers, S.A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2008-06-13
公開日2008-07-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Protein Sci., 17, 2008
2ONX
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BU of 2onx by Molmil
NNQQ peptide corresponding to residues 8-11 of yeast prion sup35 (alternate crystal form)
分子名称: peptide corresponding to residues 8-11 of yeast prion sup35
著者Sawaya, M.R, Sambashivan, S, Nelson, R, Ivanova, M, Sievers, S.A, Apostol, M.I, Thompson, M.J, Balbirnie, M, Wiltzius, J.J, McFarlane, H, Madsen, A.O, Riekel, C, Eisenberg, D.
登録日2007-01-24
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2QZV
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BU of 2qzv by Molmil
Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution
分子名称: Major vault protein
著者Anderson, D.H, Kickhoefer, V.A, Sievers, S.A, Rome, L.H, Eisenberg, D.
登録日2007-08-17
公開日2007-12-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (9 Å)
主引用文献Draft crystal structure of the vault shell at 9-A resolution.
Plos Biol., 5, 2007
3PPD
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BU of 3ppd by Molmil
GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection
分子名称: ACETIC ACID, GGVLVN peptide, amyloid forming segment, ...
著者Zhao, A, Sawaya, M.R, Eisenberg, D.
登録日2010-11-24
公開日2011-06-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.
Nature, 475, 2011
5FEC
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BU of 5fec by Molmil
Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM4deltaV1-3 gp120, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-12-16
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5FA2
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BU of 5fa2 by Molmil
Crystal structure of 426c.TM4deltaV1-3 p120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, THIOCYANATE ION, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-12-10
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
4R0P
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BU of 4r0p by Molmil
Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61
分子名称: Lysozyme C
著者Sievers, S, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
5IGX
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BU of 5igx by Molmil
Crystal structure of NIH45-46 Fab germline precursor in complex with 426c.TM1deltaV1-3 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM1deltaV1-3 gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scharf, L, Bjorkman, P.J.
登録日2016-02-28
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5I9Q
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BU of 5i9q by Molmil
Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC55 Fab heavy chain, ...
著者Scharf, L, Chen, C, Bjorkman, P.J.
登録日2016-02-20
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
3HYD
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BU of 3hyd by Molmil
LVEALYL peptide derived from human insulin chain B, residues 11-17
分子名称: Insulin
著者Ivanova, M.I, Sawaya, M.R, Eisenberg, D.
登録日2009-06-22
公開日2009-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Molecular basis for insulin fibril assembly.
Proc.Natl.Acad.Sci.USA, 106, 2009
3OVJ
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BU of 3ovj by Molmil
Structure of an amyloid forming peptide KLVFFA from amyloid beta in complex with orange G
分子名称: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, KLVFFA hexapeptide segment from Amyloid beta
著者Landau, M, Eisenberg, D.
登録日2010-09-16
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Towards a pharmacophore for amyloid.
Plos Biol., 9, 2011
3OVL
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BU of 3ovl by Molmil
Structure of an amyloid forming peptide VQIVYK from the TAU protein in complex with orange G
分子名称: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, ACETIC ACID, Microtubule-associated protein, ...
著者Landau, M, Eisenberg, D.
登録日2010-09-16
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Towards a pharmacophore for amyloid.
Plos Biol., 9, 2011
4R0W
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BU of 4r0w by Molmil
Vvtgvta, an amyloid forming segment from alpha synuclein, residues 70-76
分子名称: Alpha-synuclein
著者Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4R0U
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BU of 4r0u by Molmil
Tgvtava, an amyloid forming segment from alpha synuclein, residues 72-78
分子名称: Alpha-synuclein
著者Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
3G7W
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BU of 3g7w by Molmil
Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein
分子名称: GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ...
著者Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
登録日2009-02-11
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process
Protein Sci., 18, 2009

 

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