3PPD

GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection

Summary for 3PPD

Entry DOI	10.2210/pdb3ppd/pdb
Descriptor	GGVLVN peptide, amyloid forming segment, ZINC ION, ACETIC ACID, ... (4 entities in total)
Functional Keywords	amyloid-like protofibril, amyloid fibrils, protein fibril
Biological source	Homo sapiens (Human)
Cellular location	Isoform 1: Secreted (By similarity). Isoform 2: Lysosome membrane; Single-pass type I membrane protein: P15309
Total number of polymer chains	1
Total formula weight	683.10
Authors	Zhao, A.,Sawaya, M.R.,Eisenberg, D. (deposition date: 2010-11-24, release date: 2011-06-29, Last modification date: 2024-02-21)
Primary citation	Sievers, S.A.,Karanicolas, J.,Chang, H.W.,Zhao, A.,Jiang, L.,Zirafi, O.,Stevens, J.T.,Munch, J.,Baker, D.,Eisenberg, D. Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature, 475:96-100, 2011 Cited by PubMed: 21677644 DOI: 10.1038/nature10154 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation