6C3T

AMYLOID FORMING PEPTIDE AADTWE FROM TRANSTHYRETIN WITH ATTR-D38A MUTATION ASSOCIATED WITH A FAMILIAL FORM OF TRANSTHYRETIN AMYLOIDOSIS

Summary for 6C3T

• Entry DOI: 10.2210/pdb6c3t/pdb
• Related: 6C3F 6C3G 6C3S
• Descriptor: ALA-ALA-ASP-THR-TRP-GLU (2 entities in total)
• Functional Keywords: amyloid, transthyretin, fibril, protein fibril
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 1383.37

Authors

Sievers, S.A.,Sawaya, M.R.,Saelices, L.,Eisenberg, D.S. (deposition date: 2018-01-10, release date: 2018-04-18, Last modification date: 2024-04-03)

• Primary citation: Saelices, L.,Sievers, S.A.,Sawaya, M.R.,Eisenberg, D.S.; Crystal structures of amyloidogenic segments of human transthyretin.; Protein Sci., 27:1295-1303, 2018; PubMed: 29626847; DOI: 10.1002/pro.3420

Experimental method

X-RAY DIFFRACTION (1 Å)