5Y9J
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![BU of 5y9j by Molmil](/molmil-images/mine/5y9j) | BAFF in complex with belimumab | 分子名称: | Tumor necrosis factor ligand superfamily member 13B, belibumab light chain, belimumab heavy chain | 著者 | Heo, Y.-S, Shin, W. | 登録日 | 2017-08-25 | 公開日 | 2018-02-21 | 最終更新日 | 2019-09-04 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus. Nat Commun, 9, 2018
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5Y9K
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![BU of 5y9k by Molmil](/molmil-images/mine/5y9k) | Structure of the belimumab Fab fragment | 分子名称: | belimumab heavy chain, belimumab light chain | 著者 | Heo, Y.-S, Shin, W. | 登録日 | 2017-08-25 | 公開日 | 2018-02-21 | 最終更新日 | 2019-09-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus. Nat Commun, 9, 2018
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5WUV
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![BU of 5wuv by Molmil](/molmil-images/mine/5wuv) | Crystal structure of Certolizumab Fab | 分子名称: | heavy chain, light chain | 著者 | Heo, Y.S, Lee, J.U, Son, J.Y, Shin, W, Yoo, K.Y. | 登録日 | 2016-12-21 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases Int J Mol Sci, 18, 2017
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2A4V
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![BU of 2a4v by Molmil](/molmil-images/mine/2a4v) | Crystal Structure of a truncated mutant of yeast nuclear thiol peroxidase | 分子名称: | Peroxiredoxin DOT5 | 著者 | Choi, J, Choi, S, Chon, J.-K, Choi, J, Cha, M.-K, Kim, I.-H, Shin, W. | 登録日 | 2005-06-29 | 公開日 | 2006-03-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the C107S/C112S mutant of yeast nuclear 2-Cys peroxiredoxin Proteins, 61, 2005
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4Y7I
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![BU of 4y7i by Molmil](/molmil-images/mine/4y7i) | Crystal Structure of MTMR8 | 分子名称: | Myotubularin-related protein 8, PHOSPHATE ION | 著者 | Yoo, K, Lee, J, Son, J, Shin, W, Im, D, Heo, Y.S. | 登録日 | 2015-02-15 | 公開日 | 2015-07-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Structure of the catalytic phosphatase domain of MTMR8: implications for dimerization, membrane association and reversible oxidation. Acta Crystallogr.,Sect.D, 71, 2015
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1QXH
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![BU of 1qxh by Molmil](/molmil-images/mine/1qxh) | |
2P0M
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![BU of 2p0m by Molmil](/molmil-images/mine/2p0m) | Revised structure of rabbit reticulocyte 15S-lipoxygenase | 分子名称: | (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID, Arachidonate 15-lipoxygenase, FE (II) ION | 著者 | Choi, J, Chon, J.K, Kim, S, Shin, W. | 登録日 | 2007-02-28 | 公開日 | 2007-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data. Proteins, 70, 2008
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1IBQ
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![BU of 1ibq by Molmil](/molmil-images/mine/1ibq) | ASPERGILLOPEPSIN FROM ASPERGILLUS PHOENICIS | 分子名称: | ASPERGILLOPEPSIN, ZINC ION, alpha-D-mannopyranose | 著者 | Cho, S.W, Shin, W. | 登録日 | 2001-03-28 | 公開日 | 2001-07-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structure of aspergillopepsin I from Aspergillus phoenicis: variations of the S1'-S2 subsite in aspartic proteinases. Acta Crystallogr.,Sect.D, 57, 2001
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1IB4
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1IA5
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![BU of 1ia5 by Molmil](/molmil-images/mine/1ia5) | POLYGALACTURONASE FROM ASPERGILLUS ACULEATUS | 分子名称: | POLYGALACTURONASE, alpha-D-mannopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Cho, S.W, Lee, S, Shin, W. | 登録日 | 2001-03-22 | 公開日 | 2001-09-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The X-ray structure of Aspergillus aculeatus polygalacturonase and a modeled structure of the polygalacturonase-octagalacturonate complex. J.Mol.Biol., 311, 2001
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5WUX
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![BU of 5wux by Molmil](/molmil-images/mine/5wux) | TNFalpha-certolizumab Fab | 分子名称: | Tumor necrosis factor alpha, heavy, light | 著者 | Heo, Y.S, Lee, J.U. | 登録日 | 2016-12-21 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases Int J Mol Sci, 18, 2017
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5X02
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![BU of 5x02 by Molmil](/molmil-images/mine/5x02) | Crystal structure of the FLT3 kinase domain bound to the inhibitor FF-10101 | 分子名称: | N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide, Receptor-type tyrosine-protein kinase FLT3, SULFATE ION | 著者 | Fujikawa, N, Hirano, D, Takasaki, M, Terada, D, Hagiwara, S, Park, S.-Y, Sugiyama, K. | 登録日 | 2017-01-19 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations. Blood, 131, 2018
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5X8M
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![BU of 5x8m by Molmil](/molmil-images/mine/5x8m) | PD-L1 in complex with durvalumab | 分子名称: | Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain | 著者 | Heo, Y.S, Lee, H.T. | 登録日 | 2017-03-03 | 公開日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (2.661 Å) | 主引用文献 | Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
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5X8L
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![BU of 5x8l by Molmil](/molmil-images/mine/5x8l) | PD-L1 in complex with atezolizumab | 分子名称: | Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain | 著者 | Heo, Y.S, Lee, H.T. | 登録日 | 2017-03-03 | 公開日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
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5GGT
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![BU of 5ggt by Molmil](/molmil-images/mine/5ggt) | PD-L1 in complex with BMS-936559 Fab | 分子名称: | IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGR
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![BU of 5ggr by Molmil](/molmil-images/mine/5ggr) | PD-1 in complex with nivolumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGQ
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![BU of 5ggq by Molmil](/molmil-images/mine/5ggq) | Crystal structure of Nivolumab Fab fragment | 分子名称: | nivolumab heavy chain, nivolumab light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGV
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![BU of 5ggv by Molmil](/molmil-images/mine/5ggv) | CTLA-4 in complex with tremelimumab Fab | 分子名称: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGU
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![BU of 5ggu by Molmil](/molmil-images/mine/5ggu) | Crystal structure of tremelimumab Fab | 分子名称: | heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGS
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![BU of 5ggs by Molmil](/molmil-images/mine/5ggs) | PD-1 in complex with pembrolizumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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2CDV
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![BU of 2cdv by Molmil](/molmil-images/mine/2cdv) | REFINED STRUCTURE OF CYTOCHROME C3 AT 1.8 ANGSTROMS RESOLUTION | 分子名称: | CYTOCHROME C3, HEME C | 著者 | Higuchi, Y, Kusunoki, M, Matsuura, Y, Yasuoka, N, Kakudo, M. | 登録日 | 1983-11-15 | 公開日 | 1984-02-02 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Refined structure of cytochrome c3 at 1.8 A resolution J.Mol.Biol., 172, 1984
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