5Y9J

BAFF in complex with belimumab

Summary for 5Y9J

Entry DOI	10.2210/pdb5y9j/pdb
Descriptor	belibumab light chain, belimumab heavy chain, Tumor necrosis factor ligand superfamily member 13B, ... (4 entities in total)
Functional Keywords	baff, belimumab, antibody, lupus, protein binding
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	64803.42
Authors	Heo, Y.-S.,Shin, W. (deposition date: 2017-08-25, release date: 2018-02-21, Last modification date: 2019-09-04)
Primary citation	Shin, W.,Lee, H.T.,Lim, H.,Lee, S.H.,Son, J.Y.,Lee, J.U.,Yoo, K.Y.,Ryu, S.E.,Rhie, J.,Lee, J.Y.,Heo, Y.S. BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus. Nat Commun, 9:1200-1200, 2018 Cited by PubMed: 29572471 DOI: 10.1038/s41467-018-03620-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation