5WUX

TNFalpha-certolizumab Fab

Summary for 5WUX

• Entry DOI: 10.2210/pdb5wux/pdb
• Related: 5WUV
• Descriptor: heavy, light, Tumor necrosis factor alpha (3 entities in total)
• Functional Keywords: antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 9
• Total formula weight: 194098.43

Authors

Heo, Y.S.,Lee, J.U. (deposition date: 2016-12-21, release date: 2017-06-07)

• Primary citation: Lee, J.U.,Shin, W.,Son, J.Y.,Yoo, K.Y.,Heo, Y.S.; Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases; Int J Mol Sci, 18:-, 2017; PubMed: 28124979; DOI: 10.3390/ijms18010228

Experimental method

X-RAY DIFFRACTION (2.9 Å)