5Y9K

Structure of the belimumab Fab fragment

Summary for 5Y9K

Entry DOI	10.2210/pdb5y9k/pdb
Descriptor	belimumab light chain, belimumab heavy chain (3 entities in total)
Functional Keywords	belimumab, antibody, baff, lupus, protein binding
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	47746.97
Authors	Heo, Y.-S.,Shin, W. (deposition date: 2017-08-25, release date: 2018-02-21, Last modification date: 2019-09-04)
Primary citation	Shin, W.,Lee, H.T.,Lim, H.,Lee, S.H.,Son, J.Y.,Lee, J.U.,Yoo, K.Y.,Ryu, S.E.,Rhie, J.,Lee, J.Y.,Heo, Y.S. BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus. Nat Commun, 9:1200-1200, 2018 Cited by PubMed: 29572471 DOI: 10.1038/s41467-018-03620-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation