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KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS
分子名称:	ADENOSINE-5'-DIPHOSPHATE, KINESIN, SULFATE ION
著者	Sack, S, Muller, J, Kozielski, F, Marx, A, Thormahlen, M, Biou, V, Mandelkow, E.-M, Brady, S.T, Mandelkow, E.
登録日	1997-04-28
公開日	1998-04-08
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	X-ray structure of motor and neck domains from rat brain kinesin. Biochemistry, 36, 1997

7ALP

Severe fever with thrombocytopenia syndrome virus (Phenuiviridae) L protein
分子名称:	MAGNESIUM ION, Replicase
著者	Cusack, S, Rosenthal, M.
登録日	2020-10-07
公開日	2021-04-21
最終更新日	2024-05-15
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	Errors in the deposited SFTSV L protein structure. Nat Microbiol, 6, 2021

1H3N

Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate
分子名称:	LEUCINE, LEUCYL-TRNA SYNTHETASE, SULFATE ION, ...
著者	Cusack, S, Yaremchuk, A, Tukalo, M.
登録日	2002-09-11
公開日	2002-09-27
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	The 2A Structure of Leucyl-tRNA Synthetase and its Complex with a Leucyl-Adenylate Analogue Embo J., 19, 2000

6QCX

Crystal structure of influenza B polymerase initiation state with capped 15-mer RNA primer
分子名称:	MAGNESIUM ION, PHOSPHATE ION, PYROPHOSPHATE 2-, ...
著者	Cusack, S, Drncova, P.
登録日	2018-12-31
公開日	2019-06-05
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.08 Å)
主引用文献	Structural snapshots of actively transcribing influenza polymerase. Nat.Struct.Mol.Biol., 26, 2019

1SES

CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
分子名称:	ADENOSINE MONOPHOSPHATE, SERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE, SERYL-tRNA SYNTHETASE
著者	Cusack, S, Belrhali, H.
登録日	1994-02-21
公開日	1994-07-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate. Science, 263, 1994

1SET

CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
分子名称:	5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, SERYL-tRNA SYNTHETASE
著者	Cusack, S, Belrhali, H.
登録日	1994-02-21
公開日	1994-07-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate. Science, 263, 1994

1OBH

LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A PRE-TRANSFER EDITING SUBSTRATE ANALOGUE IN BOTH SYNTHETIC ACTIVE SITE AND EDITING SITE
分子名称:	LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, NORVALINE, ...
著者	Cusack, S, Yaremchuk, A, Tukalo, M.
登録日	2003-01-31
公開日	2003-05-09
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase Mol.Cell, 11, 2003

7ZPL

Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook
分子名称:	5' vRNA, MAGNESIUM ION, Polymerase acidic protein, ...
著者	Cusack, S, Kouba, T.
登録日	2022-04-27
公開日	2022-12-28
最終更新日	2024-07-24
実験手法	ELECTRON MICROSCOPY (3.12 Å)
主引用文献	Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023

7ZPM

Influenza A/H7N9 polymerase apo-protein dimer complex
分子名称:	Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
著者	Cusack, S, Kouba, T.
登録日	2022-04-27
公開日	2022-12-28
最終更新日	2024-07-24
実験手法	ELECTRON MICROSCOPY (2.81 Å)
主引用文献	Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023

1OBC

LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE
分子名称:	2'-AMINO-2'-DEOXYADENOSINE, LEUCINE, LEUCYL-TRNA SYNTHETASE, ...
著者	Cusack, S, Yaremchuk, A, Tukalo, M.
登録日	2003-01-30
公開日	2003-05-09
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase Mol.Cell, 11, 2003

4WSB

Bat Influenza A polymerase with bound vRNA promoter
分子名称:	Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ...
著者	Cusack, S, Pflug, A, Guilligay, D, Reich, S.
登録日	2014-10-26
公開日	2014-11-19
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.65 Å)
主引用文献	Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014

6EUX

Structure of the midlink and cap-binding domains of influenza B polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
分子名称:	(2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2
著者	Cusack, S, Gaudon, S.
登録日	2017-10-31
公開日	2017-12-13
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018

6EUV

Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)
分子名称:	(2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, NICKEL (II) ION, Polymerase basic protein 2
著者	Cusack, S, Lethier, M.
登録日	2017-10-31
公開日	2017-12-13
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018

6EUY

Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
分子名称:	(2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2, SULFATE ION
著者	Cusack, S, Gaudon, S.
登録日	2017-10-31
公開日	2017-12-13
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018

6EUW

Crystal structure of the cap-binding domain of the PB2 subunit of influenza A/H5N1 polymerase bound to an azaindazole inhibitor
分子名称:	(2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, GLYCEROL, Polymerase basic protein 2
著者	Cusack, S, Gaudon, S.
登録日	2017-10-31
公開日	2017-12-13
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1 Å)
主引用文献	Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018

7Z4O

Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
分子名称:	MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者	Cusack, S, Pflug, A.
登録日	2022-03-04
公開日	2022-05-11
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (3.412 Å)
主引用文献	Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022

7Z43

Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B
分子名称:	PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者	Cusack, S, Drncova, P.
登録日	2022-03-03
公開日	2022-05-11
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (3.123 Å)
主引用文献	Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022

7Z42

Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B
分子名称:	DNA-directed RNA polymerase II subunit RPB1, Polymerase acidic protein, Polymerase basic protein 2, ...
著者	Cusack, S, Drncova, P.
登録日	2022-03-03
公開日	2022-05-18
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.418 Å)
主引用文献	Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022

5MSG

Influenza B polymerase bound to vRNA promoter and capped RNA primer
分子名称:	PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者	Cusack, S, Guilligay, D.
登録日	2017-01-04
公開日	2017-02-08
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (3.8 Å)
主引用文献	An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase. Nucleic Acids Res., 45, 2017

6FSB

Influenza B/Memphis/13/03 endonuclease with I38T mutation
分子名称:	MAGNESIUM ION, MANGANESE (II) ION, Polymerase acidic protein
著者	Cusack, S, Speranzini, V.
登録日	2018-02-19
公開日	2018-07-11
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018

6FS7

Influenza A/California/04/2009 (pH1N1) endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
分子名称:	Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
著者	Cusack, S, Speranzini, V.
登録日	2018-02-19
公開日	2018-07-11
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1.96 Å)
主引用文献	Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018

6FS8

Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA)
分子名称:	Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein
著者	Cusack, S, Speranzini, V.
登録日	2018-02-19
公開日	2018-07-11
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018

6FS6

Influenza A/California/04/2009 (pH1N1) endonuclease with bound inhibitor, baloxavir acid (BXA)
分子名称:	Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
著者	Cusack, S, Speranzini, V.
登録日	2018-02-19
公開日	2018-07-11
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.291 Å)
主引用文献	Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018

6FS9

Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
分子名称:	Baloxavir acid, CHLORIDE ION, MANGANESE (II) ION, ...
著者	Cusack, S, Speranzini, V.
登録日	2018-02-19
公開日	2018-07-11
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.28 Å)
主引用文献	Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018

2BTE

Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue
分子名称:	2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ...
著者	Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S.
登録日	2005-05-31
公開日	2005-09-15
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation. Nat.Struct.Mol.Biol., 12, 2005

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全ヒット件数:	356
表示件数:	25
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