6FS6
Influenza A/California/04/2009 (pH1N1) endonuclease with bound inhibitor, baloxavir acid (BXA)
Summary for 6FS6
Entry DOI | 10.2210/pdb6fs6/pdb |
Descriptor | Polymerase acidic protein,Polymerase acidic protein, MANGANESE (II) ION, Baloxavir acid, ... (4 entities in total) |
Functional Keywords | influenza, endonuclease, inhibitor, viral protein |
Biological source | Influenza A virus (A/California/04/2009(H1N1)) More |
Total number of polymer chains | 6 |
Total formula weight | 138714.48 |
Authors | Cusack, S.,Speranzini, V. (deposition date: 2018-02-19, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Omoto, S.,Speranzini, V.,Hashimoto, T.,Noshi, T.,Yamaguchi, H.,Kawai, M.,Kawaguchi, K.,Uehara, T.,Shishido, T.,Naito, A.,Cusack, S. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8:9633-9633, 2018 Cited by PubMed: 29941893DOI: 10.1038/s41598-018-27890-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.291 Å) |
Structure validation
Download full validation report