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1P62
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BU of 1p62 by Molmil
Structure of human dCK complexed with gemcitabine and ADP-MG
分子名称: ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, GEMCITABINE, ...
著者Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A.
登録日2003-04-28
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
1H4H
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BU of 1h4h by Molmil
Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre
分子名称: XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose
著者Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J.
登録日2001-05-11
公開日2002-05-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase.
Chem.Biol., 6, 1999
1H4G
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BU of 1h4g by Molmil
Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre
分子名称: SULFATE ION, XYLANASE, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose
著者Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J.
登録日2001-05-11
公開日2002-05-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase.
Chem.Biol., 6, 1999
2NO9
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BU of 2no9 by Molmil
The structure of deoxycytidine kinase complexed with troxacitabine and ADP.
分子名称: 4-AMINO-1-[(2S,4S)-2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
著者Sabini, E, Lavie, A.
登録日2006-10-25
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.
Nucleic Acids Res., 35, 2007
2NOA
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BU of 2noa by Molmil
The structure of deoxycytidine kinase complexed with lamivudine and ADP.
分子名称: 4-AMINO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
著者Sabini, E, Lavie, A.
登録日2006-10-25
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.
Nucleic Acids Res., 35, 2007
2NO6
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BU of 2no6 by Molmil
C4S dCK variant of dCK in complex with FTC+ADP
分子名称: 4-AMINO-5-FLUORO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
著者Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A.
登録日2006-10-25
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
2NO0
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BU of 2no0 by Molmil
C4S dCK variant of dCK in complex with gemcitabine+ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, GEMCITABINE
著者Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A.
登録日2006-10-24
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
2NO7
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BU of 2no7 by Molmil
C4S dCK variant of dCK in complex with L-dC+ADP
分子名称: 4-AMINO-1-(2-DEOXY-BETA-L-ERYTHRO-PENTOFURANOSYL)PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
著者Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A.
登録日2006-10-25
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
2NO1
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BU of 2no1 by Molmil
C4S dCK variant of dCK in complex with D-dC+ADP
分子名称: 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
著者Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A.
登録日2006-10-24
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
2ZIA
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BU of 2zia by Molmil
C4S dCK variant of dCK in complex with cladribine+UDP
分子名称: 2-chloro-2'-deoxyadenosine, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-07-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase
J.Med.Chem., 51, 2008
2ZI7
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BU of 2zi7 by Molmil
C4S dCK variant of dCK in complex with D-dG+UDP
分子名称: 2'-DEOXY-GUANOSINE, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-07-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase
J.Med.Chem., 51, 2008
2ZI3
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BU of 2zi3 by Molmil
C4S-E247A dCK variant of dCK in complex with D-dA+ADP
分子名称: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-04-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
2ZI4
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BU of 2zi4 by Molmil
C4S dCK variant of dCK in complex with L-dA+ADP
分子名称: (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ...
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-04-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
2ZI6
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BU of 2zi6 by Molmil
C4S dCK variant of dCK in complex with D-dA+UDP
分子名称: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
2ZI9
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BU of 2zi9 by Molmil
C4S-E247A dCK variant of dCK in complex with cladribine+ADP
分子名称: 2-chloro-2'-deoxyadenosine, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-07-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase
J.Med.Chem., 51, 2008
2ZI5
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BU of 2zi5 by Molmil
C4S dCK variant of dCK in complex with L-dA+UDP
分子名称: (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者Sabini, E, Lavie, A.
登録日2008-02-13
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
1QH6
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BU of 1qh6 by Molmil
CATALYSIS AND SPECIFICITY IN ENZYMATIC GLYCOSIDE HYDROLASES: A 2,5B CONFORMATION FOR THE GLYCOSYL-ENZYME INTERMIDIATE REVEALED BY THE STRUCTURE OF THE BACILLUS AGARADHAERENS FAMILY 11 XYLANASE
分子名称: XYLANASE, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose
著者Sabini, E, Sulzenbacher, G, Dauter, M, Dauter, Z, Jorgensen, P.L, Schulein, M, Dupont, C, Davies, G.J, Wilson, K.S.
登録日1999-05-11
公開日2000-05-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Catalysis and specificity in enzymatic glycoside hydrolysis: a 2,5B conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase.
Chem.Biol., 6, 1999
1QNR
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BU of 1qnr by Molmil
The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, GLYCEROL, ...
著者Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M.
登録日1999-10-20
公開日2000-10-19
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
1QNO
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BU of 1qno by Molmil
The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE
著者Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M.
登録日1999-10-20
公開日2000-10-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
1QNP
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BU of 1qnp by Molmil
The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, GLYCEROL, ...
著者Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M.
登録日1999-10-20
公開日2000-10-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
1QNQ
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BU of 1qnq by Molmil
The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5
分子名称: 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, ...
著者Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M.
登録日1999-10-20
公開日2000-10-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
1QH7
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BU of 1qh7 by Molmil
CATALYSIS AND SPECIFICITY IN ENZYMATIC GLYCOSIDE HYDROLASES: A 2,5B CONFORMATION FOR THE GLYCOSYL-ENZYME INTERMIDIATE REVEALED BY THE STRUCTURE OF THE BACILLUS AGARADHAERENS FAMILY 11 XYLANASE
分子名称: XYLANASE, beta-D-xylopyranose
著者Sabini, E, Sulzenbacher, G, Dauter, M, Dauter, Z, Jorgensen, P.L, Schulein, M, Dupont, C, Davies, G.J, Wilson, K.S.
登録日1999-05-11
公開日2000-05-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Catalysis and specificity in enzymatic glycoside hydrolysis: a 2,5B conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase.
Chem.Biol., 6, 1999
1P60
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BU of 1p60 by Molmil
Structure of human dCK complexed with 2'-Deoxycytidine and ADP, Space group C 2 2 21
分子名称: 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase
著者Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A.
登録日2003-04-28
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
1P5Z
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BU of 1p5z by Molmil
Structure of human dCK complexed with cytarabine and ADP-MG
分子名称: ADENOSINE-5'-DIPHOSPHATE, CYTARABINE, Deoxycytidine kinase, ...
著者Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A.
登録日2003-04-28
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
1P61
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BU of 1p61 by Molmil
Structure of human dCK complexed with 2'-Deoxycytidine and ADP, P 43 21 2 space group
分子名称: 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase
著者Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A.
登録日2003-04-28
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003

 

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