8EEU
 
 | | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05 | | 分子名称: | Coat protein, Fab SKT05 heavy chain, Fab SKT05 light chain | | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | | 登録日 | 2022-09-07 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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8EEV
 | | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20 | | 分子名称: | Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain | | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | | 登録日 | 2022-09-07 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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8DEQ
 | | Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ... | | 著者 | Casner, R.G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-06-21 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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8DER
 | | Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SKV16 Fab Heavy Chain, ... | | 著者 | Casner, R.G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-06-21 | | 公開日 | 2023-06-28 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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8DUL
 | | Cryo-EM Structure of Antibody SKT05 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab SKT05 heavy chain, ... | | 著者 | Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-07-27 | | 公開日 | 2023-07-05 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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8DUN
 | | Cryo-EM Structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody SKW11 heavy chain, ... | | 著者 | Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-07-27 | | 公開日 | 2023-07-05 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (5.84 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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5K9J
 | | Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization. | | 分子名称: | 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34) | | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | | 登録日 | 2016-05-31 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
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3SE9
 | | Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 | | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kwong, P.D, Zhou, T. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
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3SE8
 | | Crystal structure of broadly and potently neutralizing antibody VRC03 in complex with HIV-1 gp120 | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kwong, P.D, Zhou, T. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
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5WHZ
 | | PGDM1400-10E8v4 CODV Fab | | 分子名称: | Anti-HIV CODV-Fab Heavy chain, Anti-HIV CODV-Fab Light chain | | 著者 | Lord, D.M, Wei, R.R. | | 登録日 | 2017-07-18 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.549 Å) | | 主引用文献 | Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Science, 358, 2017
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4OLX
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6CEZ
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6TYB
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7TB4
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6XRT
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6XCJ
 | | Crystal Structure of DH650 Fab from a Rhesus Macaque in Complex with HIV-1 gp120 Core | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH650 Fab Heavy Chain, DH650 Fab Light Chain, ... | | 著者 | Raymond, D.D, Chug, H, Harrison, S.C. | | 登録日 | 2020-06-08 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.
Science, 371, 2021
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8SW4
 | | BG505 GT1.1 SOSIP in complex with NHP Fabs 21N13, 21M20 and RM20A3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21M20 heavy chain variable region, ... | | 著者 | Ozorowski, G, Torres, J.L, Zhang, S, Ward, A.B. | | 登録日 | 2023-05-17 | | 公開日 | 2024-05-29 | | 最終更新日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.
Sci Immunol, 9, 2024
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8SW3
 | | BG505 GT1.1 SOSIP in complex with NHP Fabs 12C11 and RM20A3 | | 分子名称: | 12C11 heavy chain variable region, 12C11 light chain variable region, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, S, Torres, J.L, Ozorowski, G, Ward, A.B. | | 登録日 | 2023-05-17 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.
Sci Immunol, 9, 2024
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7LRT
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7LRS
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7MM0
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B1-182.1 Fab heavy chain, ... | | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | | 登録日 | 2021-04-29 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
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7MLZ
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain | | 分子名称: | B1-182.1 Fab heavy chain, B1-182.1 Fab light chain, Spike protein S1, ... | | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | | 登録日 | 2021-04-29 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
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5K9K
 | | Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 in complex with Hemagglutinin Hong Kong 1968. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 56.a.09 Heavy chain, ... | | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | | 登録日 | 2016-05-31 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
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5KAN
 | | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.g.07 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | | 分子名称: | 16.g.07 Heavy chain, 16.g.07 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | | 登録日 | 2016-06-01 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.785 Å) | | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell(Cambridge,Mass.), 166, 2016
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5KAQ
 | | Crystal structure of broadly neutralizing Influenza A antibody 31.a.83 in complex with Hemagglutinin Hong Kong 1968. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 31.A.83 FAB HEAVY CHAIN, ANTIBODY 31.A.83 FAB LIGHT CHAIN, ... | | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | | 登録日 | 2016-06-01 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.514 Å) | | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
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