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5WHZ

PGDM1400-10E8v4 CODV Fab

Summary for 5WHZ
Entry DOI10.2210/pdb5whz/pdb
DescriptorAnti-HIV CODV-Fab Light chain, Anti-HIV CODV-Fab Heavy chain (2 entities in total)
Functional Keywordscross-over dual variable immunoglobin, multifunctional biotherapeutic format, bispecific property, codv, hiv, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains2
Total formula weight80401.19
Authors
Lord, D.M.,Wei, R.R. (deposition date: 2017-07-18, release date: 2017-10-11, Last modification date: 2023-10-04)
Primary citationXu, L.,Pegu, A.,Rao, E.,Doria-Rose, N.,Beninga, J.,McKee, K.,Lord, D.M.,Wei, R.R.,Deng, G.,Louder, M.,Schmidt, S.D.,Mankoff, Z.,Wu, L.,Asokan, M.,Beil, C.,Lange, C.,Leuschner, W.D.,Kruip, J.,Sendak, R.,Do Kwon, Y.,Zhou, T.,Chen, X.,Bailer, R.T.,Wang, K.,Choe, M.,Tartaglia, L.J.,Barouch, D.H.,O'Dell, S.,Todd, J.P.,Burton, D.R.,Roederer, M.,Connors, M.,Koup, R.A.,Kwong, P.D.,Yang, Z.Y.,Mascola, J.R.,Nabel, G.J.
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Science, 358:85-90, 2017
Cited by
PubMed: 28931639
DOI: 10.1126/science.aan8630
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.549 Å)
Structure validation

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