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4IRG
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BU of 4irg by Molmil
Uninhibited DNA-binding domain of the Ets transcription factor ERG
分子名称: Transcriptional regulator ERG
著者Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
登録日2013-01-14
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IRH
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BU of 4irh by Molmil
Auto-inhibited ERG Ets domain
分子名称: Transcriptional regulator ERG
著者Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
登録日2013-01-14
公開日2013-07-31
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IRI
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BU of 4iri by Molmil
Auto-inhibited ERG Ets Domain-DNA Complex
分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*G)-3'), Transcriptional regulator ERG
著者Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
登録日2013-01-14
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
6E7R
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BU of 6e7r by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7T
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BU of 6e7t by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7S
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BU of 6e7s by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7U
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BU of 6e7u by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-31
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7X
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BU of 6e7x by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-97
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7V
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BU of 6e7v by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-88
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7W
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BU of 6e7w by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-115
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
8G18
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BU of 8g18 by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-108
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ...
著者Regan, M.C, Furukawa, H.
登録日2023-02-01
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model.
Acs Chem Neurosci, 14, 2023
6CNA
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BU of 6cna by Molmil
GluN1-GluN2B NMDA receptors with exon 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Furukawa, H, Grant, T, Grigorieff, N.
登録日2018-03-07
公開日2018-10-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
7TE6
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BU of 7te6 by Molmil
Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Regan, M, Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.55 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
5OJK
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BU of 5ojk by Molmil
Crystal structure of the human neuroligin 1 cholinesterase domain containing spliced sequence B (SSB) (NL1(-A+B))
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-1,Neuroligin-1, TRIETHYLENE GLYCOL
著者Elegheert, J, Aricescu, A.R.
登録日2017-07-21
公開日2017-08-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Neuron, 95, 2017
5OJ6
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BU of 5oj6 by Molmil
Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1 (NL1(-A-B)) cholinesterase domain.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, Neuroligin-1, ...
著者Elegheert, J, Clayton, A.J, Aricescu, A.R.
登録日2017-07-20
公開日2017-08-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Neuron, 95, 2017
5OJ2
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BU of 5oj2 by Molmil
Crystal structure of the chicken MDGA1 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Elegheert, J, Clayton, A.J, Aricescu, A.R.
登録日2017-07-20
公開日2017-08-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Neuron, 95, 2017
7TE4
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BU of 7te4 by Molmil
Crystal structure of Fab2 anti-GluN2B antibody
分子名称: Fab anti-GluN2B antibody, heavy chain, Fab2 anti-GluN2B antibody, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.456 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEB
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BU of 7teb by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like
分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TER
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BU of 7ter by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (5.23 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEE
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BU of 7tee by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like
分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (6.59 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TET
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BU of 7tet by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.45 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEQ
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BU of 7teq by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (7.51 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TE9
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BU of 7te9 by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1
分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TES
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BU of 7tes by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022

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