5OJ2

Crystal structure of the chicken MDGA1 ectodomain

Summary for 5OJ2

Entry DOI	10.2210/pdb5oj2/pdb
Descriptor	MAM domain-containing glycosylphosphatidylinositol anchor protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	neuroligin-neurexin, synapse formation, austism spectrum disorders (asds), synaptic transmission, cell adhesion
Biological source	Gallus gallus (Chicken)
Cellular location	Cell membrane ; Lipid-anchor, GPI-anchor : Q0WYX8
Total number of polymer chains	2
Total formula weight	210348.00
Authors	Elegheert, J.,Clayton, A.J.,Aricescu, A.R. (deposition date: 2017-07-20, release date: 2017-08-23, Last modification date: 2020-07-29)
Primary citation	Elegheert, J.,Cvetkovska, V.,Clayton, A.J.,Heroven, C.,Vennekens, K.M.,Smukowski, S.N.,Regan, M.C.,Jia, W.,Smith, A.C.,Furukawa, H.,Savas, J.N.,de Wit, J.,Begbie, J.,Craig, A.M.,Aricescu, A.R. Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron, 95:896-913.e10, 2017 Cited by PubMed: 28817804 DOI: 10.1016/j.neuron.2017.07.040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation