4FHQ
 
 | | Crystal Structure of HVEM | | 分子名称: | Tumor necrosis factor receptor superfamily member 14 | | 著者 | Liu, W, Zhan, C, Patskovsky, Y, Bhosle, R.C, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-06-06 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
Mol Biotechnol, 57, 2015
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3BP5
 | | Crystal structure of the mouse PD-1 and PD-L2 complex | | 分子名称: | GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-12-18 | | 公開日 | 2008-07-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BOV
 | | Crystal structure of the receptor binding domain of mouse PD-L2 | | 分子名称: | FORMIC ACID, Programmed cell death 1 ligand 2, SODIUM ION | | 著者 | Lazar-Molnar, E, Ramagopal, U, Cao, E, Toro, R, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-12-17 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.USA, 105, 2008
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3BP6
 | | Crystal structure of the mouse PD-1 Mutant and PD-L2 complex | | 分子名称: | GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-12-18 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the mouse PD-1 A99L and PD-L2 complex
To be published
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2R32
 | | Crystal Structure of human GITRL variant | | 分子名称: | GCN4-pII/Tumor necrosis factor ligand superfamily member 18 fusion protein, SULFATE ION | | 著者 | Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-08-28 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proc.Natl.Acad.Sci.USA, 104, 2007
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2R30
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3K51
 | | Crystal Structure of DcR3-TL1A complex | | 分子名称: | Decoy receptor 3, Tumor necrosis factor ligand superfamily member 15, secreted form | | 著者 | Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | | 登録日 | 2009-10-06 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
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3B9I
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1DQT
 | | THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4 | | 著者 | Ostrov, D.A, Shi, W, Schwartz, J.C, Almo, S.C, Nathenson, S.G. | | 登録日 | 2000-01-05 | | 公開日 | 2000-10-27 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of murine CTLA-4 and its role in modulating T cell responsiveness.
Science, 290, 2000
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1NCN
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2IF7
 | | Crystal Structure of NTB-A | | 分子名称: | CALCIUM ION, CHLORIDE ION, SLAM family member 6 | | 著者 | Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C. | | 登録日 | 2006-09-20 | | 公開日 | 2006-10-17 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
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2RJK
 | | Crystal Structure of Human TL1A Extracellular Domain C95S Mutant | | 分子名称: | TNF superfamily ligand TL1A | | 著者 | Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Ramagopal, U.A, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-10-15 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
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2RJL
 | | Crystal structure of human TL1A extracellular domain C95S/C135S mutant | | 分子名称: | TNF superfamily ligand TL1A | | 著者 | Zhan, C, Patskovsky, Y, Yan, Q, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-10-15 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
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3MI8
 | | The structure of TL1A-DCR3 COMPLEX | | 分子名称: | TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM, Tumor necrosis factor receptor superfamily member 6B | | 著者 | Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | | 登録日 | 2010-04-09 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.951 Å) | | 主引用文献 | Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
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3MHD
 | | Crystal structure of DCR3 | | 分子名称: | Tumor necrosis factor receptor superfamily member 6B | | 著者 | Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | | 登録日 | 2010-04-07 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | | 主引用文献 | Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
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3NWM
 | | Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes | | 分子名称: | Peptide/beta-2microglobulin/MHC class I H-2Kd chimeric protein | | 著者 | Ramagopal, U.A, Samanta, D, Nathenson, S.G, Almo, S.C. | | 登録日 | 2010-07-09 | | 公開日 | 2011-07-06 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4G4F
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1NPU
 | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1 | | 分子名称: | Programmed cell death protein 1 | | 著者 | Zhang, X, Schwartz, J.-C.D, Guo, X, Cao, E, Chen, L, Zhang, Z.-Y, Nathenson, S.G, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2003-01-20 | | 公開日 | 2004-03-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity, 20, 2004
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4I0K
 | | Crystal structure of murine B7-H3 extracellular domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD276 antigen, SULFATE ION, ... | | 著者 | Vigdorovich, V, Ramagopal, U, Bonanno, J.B, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | | 登録日 | 2012-11-16 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Structure and T cell inhibition properties of B7 family member, B7-H3.
Structure, 21, 2013
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4HWN
 | | Crystal structure of the second Ig-C2 domain of human Fc-receptor like A (FCRLA), Isoform 9 [NYSGRC-005836] | | 分子名称: | Fc receptor-like A | | 著者 | Kumar, P.R, Ahmed, M, Bhosle, R, Calarese, D, Celikigil, A, Chan, M.K, Fiser, A, Garforth, S, Glenn, A.S, Hillerich, B, Khafizov, K, Love, J, Patel, H, Rubinstein, R, Seidel, R, Stead, M, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | | 登録日 | 2012-11-08 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Crystal structure of the second Ig-C2 domain of the human Fc-receptor like A, Isoform 9 [NYSGRC-005836]
to be published
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4HWU
 | | Crystal structure of the Ig-C2 type 1 domain from mouse Fibroblast growth factor receptor 2 (FGFR2) [NYSGRC-005912] | | 分子名称: | Fibroblast growth factor receptor 2 | | 著者 | Kumar, P.R, Ahmed, M, Banu, R, Bhosle, R, Calarese, D, Celikigil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S, Glenn, A.S, Hillerich, B, Khafizov, K, Love, J, Patel, H, Rubinstein, R, Seidel, R, Stead, M, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | | 登録日 | 2012-11-08 | | 公開日 | 2012-11-21 | | 実験手法 | X-RAY DIFFRACTION (2.903 Å) | | 主引用文献 | Crystal structure of the Ig-C2 type 1 domain from mouse FGFR2 [NYSGRC-005912]
to be published
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4HZA
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1INQ
 | | Structure of Minor Histocompatibility Antigen peptide, H13a, complexed to H2-Db | | 分子名称: | BETA-2 MICROGLOBULIN, DIMETHYL SULFOXIDE, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D, Nathenson, S.G. | | 登録日 | 2001-05-14 | | 公開日 | 2002-03-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
J.Immunol., 168, 2002
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1I85
 | | CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX | | 分子名称: | CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD86 | | 著者 | Schwartz, J.-C.D, Zhang, X, Fedorov, A.A, Nathenson, S.G, Almo, S.C. | | 登録日 | 2001-03-12 | | 公開日 | 2001-04-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.
Nature, 410, 2001
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1JUF
 | | Structure of Minor Histocompatibility Antigen peptide, H13b, complexed to H2-Db | | 分子名称: | Beta-2-microglobulin, H13b peptide, H2-Db major histocompatibility antigen | | 著者 | Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D.C, Nathenson, S.G. | | 登録日 | 2001-08-24 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
J.Immunol., 168, 2002
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