2R32

Crystal Structure of human GITRL variant

Summary for 2R32

• Entry DOI: 10.2210/pdb2r32/pdb
• Related: 2R30 2q1m
• Descriptor: GCN4-pII/Tumor necrosis factor ligand superfamily member 18 fusion protein, SULFATE ION (3 entities in total)
• Functional Keywords: gitrl, glucocorticoid-induced tnf receptor ligand, cytokine, glycoprotein, membrane, signal-anchor, transmembrane, immune system
• Biological source: Saccharomyces cerevisiae, Homo sapiens (baker's yeast, human)
• Cellular location: Cell membrane ; Single-pass type II membrane protein : Q9UNG2
• Total number of polymer chains: 1
• Total formula weight: 19013.78

Authors

Chattopadhyay, K.,Ramagopal, U.A.,Nathenson, S.G.,Almo, S.C. (deposition date: 2007-08-28, release date: 2007-11-20, Last modification date: 2023-08-30)

• Primary citation: Chattopadhyay, K.,Ramagopal, U.A.,Mukhopadhaya, A.,Malashkevich, V.N.,Dilorenzo, T.P.,Brenowitz, M.,Nathenson, S.G.,Almo, S.C.; Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.; Proc.Natl.Acad.Sci.USA, 104:19452-19457, 2007; PubMed: 18040044; DOI: 10.1073/pnas.0709264104

Experimental method

X-RAY DIFFRACTION (1.95 Å)