1DQT

THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152)

Summary for 1DQT

• Entry DOI: 10.2210/pdb1dqt/pdb
• Descriptor: CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4, CHLORIDE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: immunoglobulin variable domain-like beta-sandwich, homodimer, immune system
• Biological source: Mus musculus (house mouse)
• Cellular location: Cell membrane ; Single-pass type I membrane protein : P09793
• Total number of polymer chains: 4
• Total formula weight: 51914.06

Authors

Ostrov, D.A.,Shi, W.,Schwartz, J.C.,Almo, S.C.,Nathenson, S.G. (deposition date: 2000-01-05, release date: 2000-10-27, Last modification date: 2018-01-31)

• Primary citation: Ostrov, D.A.,Shi, W.,Schwartz, J.C.,Almo, S.C.,Nathenson, S.G.; Structure of murine CTLA-4 and its role in modulating T cell responsiveness.; Science, 290:816-819, 2000; PubMed: 11052947; DOI: 10.1126/science.290.5492.816

Experimental method

X-RAY DIFFRACTION (2 Å)