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8YJ8
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BU of 8yj8 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, VHH43, ZINC ION
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
8YJ5
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BU of 8yj5 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, VHH43
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
8YJ7
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BU of 8yj7 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, ZINC ION, scFv13
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
8YJ6
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BU of 8yj6 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, ZINC ION
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
3WII
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BU of 3wii by Molmil
Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1.
分子名称: anti-human ROBO1 antibody B2212A Fab heavy chain, anti-human ROBO1 antibody B2212A Fab light chain
著者Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, S, Nakakido, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T.
登録日2013-09-12
公開日2015-01-21
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
8GQ1
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BU of 8gq1 by Molmil
HyHEL10 Fab complexed with hen egg lysozyme carrying arginine cluster in framework region of light chain.
分子名称: Heavy Chain of HyHel10 Antibody Fragment (Fab), Light Chain of HyHel10 Antibody Fragment (Fab), Lysozyme C, ...
著者Matsuura, H, Hirata, K, Sakai, N, Nakakido, M, Tsumoto, K.
登録日2022-08-28
公開日2023-08-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Arginine cluster introduction on framework region in anti-lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops.
Protein Sci., 32, 2023
7XL0
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BU of 7xl0 by Molmil
Crystal structure of Vobarilizumab at 1.70 Angstrom
分子名称: GLYCEROL, Nanobody Vobarilizumab, SULFATE ION
著者Caaveiro, J.M.M, Mori, C, Kinoshita, S, Nakakido, M, Tsumoto, K.
登録日2022-04-20
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3.
Protein Sci., 31, 2022
7XL1
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BU of 7xl1 by Molmil
Crystal structure of chimeric 7D12-Vob nanobody at 1.65 Angstrom
分子名称: Chimeric 7D12-Vob nanobody, MALONATE ION
著者Caaveiro, J.M.M, Kinoshita, S, Mori, C, Nakakido, M, Tsumoto, K.
登録日2022-04-20
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3.
Protein Sci., 31, 2022
7XLD
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BU of 7xld by Molmil
Crystal structure of IsdH linker-NEAT3 bound to a nanobody (VHH)
分子名称: Iron-regulated surface determinant protein H, MAGNESIUM ION, Nanobody VHH6, ...
著者Caaveiro, J.M.M, Valenciano-Bellido, S, Tsumoto, K.
登録日2022-04-21
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth.
J.Biol.Chem., 299, 2023
8YX9
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BU of 8yx9 by Molmil
CD40 in complex with Dacetuzumab Fab
分子名称: Dacetuzumab, Heavy chain, light chain, ...
著者Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K.
登録日2024-04-02
公開日2024-05-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
8YX1
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BU of 8yx1 by Molmil
CD40 in complex with Bleselumab Fab
分子名称: Bleselumab, heavy chain, light chain, ...
著者Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K.
登録日2024-04-01
公開日2024-05-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
6LDX
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BU of 6ldx by Molmil
Structure antibody E6 in complex with methylated peptide
分子名称: CHLORIDE ION, Fab Heavy chain, Fab light chain, ...
著者Caaveiro, J.M.M, Tsumoto, K.
登録日2019-11-23
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
6LDY
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BU of 6ldy by Molmil
Structure antibody D6 in complex with methylated peptide
分子名称: CALCIUM ION, CHLORIDE ION, Fab heavy chain, ...
著者Caaveiro, J.M.M, Tsumoto, K.
登録日2019-11-23
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
6LDW
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BU of 6ldw by Molmil
Structure of antibody C9 in complex with methylated peptide
分子名称: CHLORIDE ION, Fab heavy chain, Fab light chain, ...
著者Caaveiro, J.M.M, Tsumoto, K.
登録日2019-11-23
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
6LDV
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BU of 6ldv by Molmil
Structure antibody F9 in complex with methylated peptide
分子名称: Fab heavy chain, Fab light chain, GLY-M3L-GLY-GLY-THR-TYR-PRO, ...
著者Caaveiro, J.M.M, Tsumoto, K.
登録日2019-11-23
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
3WIH
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BU of 3wih by Molmil
Crystal structure of the third fibronectin domain (Fn3) of human ROBO1 in complex with the Fab fragment of murine monoclonal antibody B2212A.
分子名称: GLYCEROL, Roundabout homolog 1, anti-human ROBO1 antibody B2212A Fab heavy chain, ...
著者Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T.
登録日2013-09-12
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
7CUE
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BU of 7cue by Molmil
Crystal structure of HID2 bound to human Hemoglobin
分子名称: Amino acid ABC transporter substrate-binding protein, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Caaveiro, J.M.M, Hoshino, M, Tsumoto, K.
登録日2020-08-22
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for the recognition of human hemoglobin by the Shr protein from Streptococcus pyogenes
To Be Published
7CUD
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BU of 7cud by Molmil
Crystal structure of HID in the unbound form
分子名称: Amino acid ABC transporter substrate-binding protein, BROMIDE ION
著者Caaveiro, J.M.M, Hoshino, M, Tsumoto, K.
登録日2020-08-22
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the recognition of human hemoglobin by the Shr protein from Streptococcus pyogenes
To Be Published
7WKI
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BU of 7wki by Molmil
Structure of the ultra-affinity complex between CFH and a nanobody
分子名称: Anti-CFH nanobody (VHH), Complement factor H
著者Caaveiro, J.M.M, Yokoo, T, Tsumoto, K.
登録日2022-01-10
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis.
J.Biol.Chem., 298, 2022
8H63
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BU of 8h63 by Molmil
Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH10 bound
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K.
登録日2022-10-15
公開日2023-10-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
J.Biol.Chem., 299, 2023
8H64
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BU of 8h64 by Molmil
Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH24 bound
分子名称: Anti-internalin A VHH24, CHLORIDE ION, Internalin A
著者Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K.
登録日2022-10-15
公開日2023-10-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
J.Biol.Chem., 299, 2023
8H62
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BU of 8h62 by Molmil
Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12
分子名称: ACETATE ION, CALCIUM ION, Cadherin-1, ...
著者Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K.
登録日2022-10-14
公開日2023-10-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
J.Biol.Chem., 299, 2023
8JOW
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BU of 8jow by Molmil
Crystal structure of rabbit antibody with phosphorylated peptide bound
分子名称: ARG-PRO-HIS-PHE-PRO-GLN-PHE-SEP-TYR-SER-ALA-SER, Antibody (scFv), CHLORIDE ION
著者Caaveiro, J.M.M, Kawade, R, Tsumoto, K.
登録日2023-06-08
公開日2024-06-12
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Origin of high binding affinity and selectivity of phosphorylated epitope-specific rabbit antibodies
To Be Published
7EV1
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BU of 7ev1 by Molmil
Crystal structure of LI-Cadherin EC1-2
分子名称: ACETATE ION, CALCIUM ION, Cadherin-17, ...
著者Caaveiro, J.M.M, Yui, A, Tsumoto, K.
登録日2021-05-19
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021
7CYM
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BU of 7cym by Molmil
Crystal structure of LI-Cadherin EC1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Caaveiro, J.M.M, Yui, A, Tsumoto, K.
登録日2020-09-03
公開日2021-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021

 

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