8GQ1

HyHEL10 Fab complexed with hen egg lysozyme carrying arginine cluster in framework region of light chain.

Summary for 8GQ1

• Entry DOI: 10.2210/pdb8gq1/pdb
• Descriptor: Lysozyme C, Light Chain of HyHel10 Antibody Fragment (Fab), Heavy Chain of HyHel10 Antibody Fragment (Fab), ... (4 entities in total)
• Functional Keywords: engineered antibody, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 63490.59

Authors

Matsuura, H.,Hirata, K.,Sakai, N.,Nakakido, M.,Tsumoto, K. (deposition date: 2022-08-28, release date: 2023-08-30, Last modification date: 2024-03-13)

• Primary citation: Maeta, S.,Nakakido, M.,Matsuura, H.,Sakai, N.,Hirata, K.,Kuroda, D.,Fukunaga, A.,Tsumoto, K.; Arginine cluster introduction on framework region in anti-lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops.; Protein Sci., 32:e4745-e4745, 2023; PubMed: 37550885; DOI: 10.1002/pro.4745

Experimental method

X-RAY DIFFRACTION (3.13 Å)