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5GJE
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BU of 5gje by Molmil
Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J.
登録日2016-06-29
公開日2017-01-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (21 Å)
主引用文献Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1
Cell Rep, 18, 2017
6AHY
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BU of 6ahy by Molmil
Wnt signaling complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Hirai, H, Arimori, T, Matoba, K, Mihara, E, Takagi, J.
登録日2018-08-21
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a mammalian Wnt-frizzled complex.
Nat.Struct.Mol.Biol., 26, 2019
3NKM
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BU of 3nkm by Molmil
Crystal structure of mouse autotaxin
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
登録日2010-06-20
公開日2011-01-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKN
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BU of 3nkn by Molmil
Crystal structure of mouse autotaxin in complex with 14:0-LPA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
登録日2010-06-20
公開日2011-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKQ
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BU of 3nkq by Molmil
Crystal structure of mouse autotaxin in complex with 18:3-LPA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E,12Z,15Z)-octadeca-9,12,15-trienoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
登録日2010-06-20
公開日2011-01-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKP
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BU of 3nkp by Molmil
Crystal structure of mouse autotaxin in complex with 18:1-LPA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
登録日2010-06-20
公開日2011-01-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKR
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BU of 3nkr by Molmil
Crystal structure of mouse autotaxin in complex with 22:6-LPA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (4Z,7E,10E,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
登録日2010-06-20
公開日2011-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.704 Å)
主引用文献Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKO
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BU of 3nko by Molmil
Crystal structure of mouse autotaxin in complex with 16:0-LPA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
登録日2010-06-20
公開日2011-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3AL9
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BU of 3al9 by Molmil
Mouse Plexin A2 extracellular domain
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2
著者Nogi, T, Yasui, N, Mihara, E, Takagi, J.
登録日2010-07-28
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for semaphorin signalling through the plexin receptor.
Nature, 467, 2010
3AFC
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BU of 3afc by Molmil
Mouse Semaphorin 6A extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-6A
著者Yasui, N, Nogi, T, Mihara, E, Takagi, J.
登録日2010-02-26
公開日2010-10-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for semaphorin signalling through the plexin receptor.
Nature, 467, 2010
3AL8
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BU of 3al8 by Molmil
Plexin A2 / Semaphorin 6A complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2, ...
著者Nogi, T, Yasui, N, Mihara, E, Takagi, J.
登録日2010-07-28
公開日2010-10-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis for semaphorin signalling through the plexin receptor.
Nature, 467, 2010
7Y4P
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BU of 7y4p by Molmil
Human Plexin A1, extracellular domains 1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
7Y4O
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BU of 7y4o by Molmil
Rat Semaphorin 6D extracellular region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin 6D
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
7Y4Q
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BU of 7y4q by Molmil
Semaphorin 6D in complex with Plexin A1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, ...
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-16
公開日2022-10-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
8JYR
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BU of 8jyr by Molmil
Crystal structure of anti-HER2 antibody H2Mab-119 in complex with HER2 domain I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H2Mab-119 VH-CH1, H2Mab-119 light chain, ...
著者Arimori, T, Takagi, J.
登録日2023-07-03
公開日2024-03-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
8JYQ
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BU of 8jyq by Molmil
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide
分子名称: H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide
著者Arimori, T, Takagi, J.
登録日2023-07-03
公開日2024-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
5EGH
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BU of 5egh by Molmil
Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J.
登録日2015-10-27
公開日2016-03-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Sci Rep, 6, 2016
5EGE
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BU of 5ege by Molmil
Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J.
登録日2015-10-27
公開日2016-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Sci Rep, 6, 2016
7DMU
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BU of 7dmu by Molmil
Structure of SARS-CoV-2 spike receptor-binding domain complexed with high affinity ACE2 mutant 3N39
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Arimori, T, Takagi, J.
登録日2020-12-07
公開日2020-12-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Nat Commun, 12, 2021
5ZIC
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BU of 5zic by Molmil
Crystal structure of human GnT-V luminal domain in complex with acceptor sugar
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-6-thio-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
著者Nagae, M, Yamaguchi, Y.
登録日2018-03-14
公開日2018-08-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
Nat Commun, 9, 2018
5ZIB
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BU of 5zib by Molmil
Crystal structure of human GnT-V luminal domain in apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
著者Nagae, M, Yamaguchi, Y.
登録日2018-03-14
公開日2018-08-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
Nat Commun, 9, 2018
4GTW
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BU of 4gtw by Molmil
Crystal structure of mouse Enpp1 in complex with AMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTZ
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BU of 4gtz by Molmil
Crystal structure of mouse Enpp1 in complex with CMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.191 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTY
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BU of 4gty by Molmil
Crystal structure of mouse Enpp1 in complex with GMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTX
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Crystal structure of mouse Enpp1 in complex with TMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.201 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012

 

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