8JYQ
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide
Summary for 8JYQ
| Entry DOI | 10.2210/pdb8jyq/pdb |
| Descriptor | H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide, ... (4 entities in total) |
| Functional Keywords | her2, antibody, immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 6 |
| Total formula weight | 79470.36 |
| Authors | Arimori, T.,Takagi, J. (deposition date: 2023-07-03, release date: 2024-03-13, Last modification date: 2024-03-27) |
| Primary citation | Arimori, T.,Mihara, E.,Suzuki, H.,Ohishi, T.,Tanaka, T.,Kaneko, M.K.,Takagi, J.,Kato, Y. Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies. Structure, 2024 Cited by PubMed: 38460519DOI: 10.1016/j.str.2024.02.007 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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