3NKM

Crystal structure of mouse autotaxin

Summary for 3NKM

Related3NKN 3NKO 3NKP 3NKQ 3NKR
DescriptorEctonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... (13 entities in total)
Functional Keywordslysophospholipase d, autotaxin, enpp2, lysophosphatidic acid, hydrolase
Biological sourceMus musculus (mouse)
Cellular locationSecreted  Q9R1E6
Total number of polymer chains1
Total molecular weight99742.19
Authors
Nishimasu, H.,Ishitani, R.,Mihara, E.,Takagi, J.,Aoki, J.,Nureki, O. (deposition date: 2010-06-20, release date: 2011-01-19, Last modification date: 2017-11-08)
Primary citation
Nishimasu, H.,Okudaira, S.,Hama, K.,Mihara, E.,Dohmae, N.,Inoue, A.,Ishitani, R.,Takagi, J.,Aoki, J.,Nureki, O.
Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18:205-212, 2011
PubMed: 21240269 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.1998
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.002 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20860.4%0.6%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3nkm
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Molmil generated image of 3nkm
rotated about x axis by 90°
Molmil generated image of 3nkm
rotated about y axis by 90°