5ZIC

Crystal structure of human GnT-V luminal domain in complex with acceptor sugar

Summary for 5ZIC

• Entry DOI: 10.2210/pdb5zic/pdb
• Related: 5ZIB
• Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-6-thio-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose (3 entities in total)
• Functional Keywords: glycosyltransferase cancer metastasis luminal protein, sugar binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 120720.71

Authors

Nagae, M.,Yamaguchi, Y. (deposition date: 2018-03-14, release date: 2018-08-01, Last modification date: 2023-11-22)

• Primary citation: Nagae, M.,Kizuka, Y.,Mihara, E.,Kitago, Y.,Hanashima, S.,Ito, Y.,Takagi, J.,Taniguchi, N.,Yamaguchi, Y.; Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.; Nat Commun, 9:3380-3380, 2018; PubMed: 30140003; DOI: 10.1038/s41467-018-05931-w

Experimental method

X-RAY DIFFRACTION (2.1 Å)