5EGH

Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine

Summary for 5EGH

• Entry DOI: 10.2210/pdb5egh/pdb
• Related: 5EGE
• Descriptor: Ectonucleotide pyrophosphatase/phosphodiesterase family member 6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: choline metabolism, phosphodiesterase, hydrolase
• Biological source: Mus musculus (Mouse)
• Cellular location: Cell membrane ; Lipid-anchor, GPI-anchor : Q8BGN3
• Total number of polymer chains: 2
• Total formula weight: 102773.10

Authors

Morita, J.,Kano, K.,Kato, K.,Takita, H.,Ishitani, R.,Nishimasu, H.,Nureki, O.,Aoki, J. (deposition date: 2015-10-27, release date: 2016-03-09, Last modification date: 2020-07-29)

• Primary citation: Morita, J.,Kano, K.,Kato, K.,Takita, H.,Sakagami, H.,Yamamoto, Y.,Mihara, E.,Ueda, H.,Sato, T.,Tokuyama, H.,Arai, H.,Asou, H.,Takagi, J.,Ishitani, R.,Nishimasu, H.,Nureki, O.,Aoki, J.; Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase; Sci Rep, 6:20995-20995, 2016; PubMed: 26888014; DOI: 10.1038/srep20995

Experimental method

X-RAY DIFFRACTION (1.803 Å)