8BVF
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![BU of 8bvf by Molmil](/molmil-images/mine/8bvf) | MoeA2 from Corynebacterium glutamicum in complex with FtsZ-CTD | 分子名称: | Cell division protein FtsZ, Molybdopterin molybdenumtransferase, SODIUM ION, ... | 著者 | Martinez, M, Haouz, A, Wehenkel, A.M, Alzari, P.M. | 登録日 | 2022-12-03 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation. Biorxiv, 2023
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8BVE
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![BU of 8bve by Molmil](/molmil-images/mine/8bve) | MoeA2 from Corynebacterium glutamicum | 分子名称: | CITRIC ACID, Molybdopterin molybdenumtransferase, SODIUM ION | 著者 | Martinez, M, Haouz, A, Wehenkel, A.M, Alzari, P.M. | 登録日 | 2022-12-03 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation. Biorxiv, 2023
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8COY
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![BU of 8coy by Molmil](/molmil-images/mine/8coy) | Structure of the catalytic domain of P. vivax Sub1 (triclinic crystal form) in complex with inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SULFATE ION, ... | 著者 | Martinez, M, Bouillon, A, Batista, F, Alzari, P.M, Barale, J.C, Haouz, A. | 登録日 | 2023-03-01 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.507 Å) | 主引用文献 | 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived alpha-ketoamide inhibitor. Acta Crystallogr D Struct Biol, 79, 2023
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8CP0
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![BU of 8cp0 by Molmil](/molmil-images/mine/8cp0) | Structure of the catalytic domain of P. vivax Sub1 (trigonal crystal form) | 分子名称: | CALCIUM ION, subtilisin | 著者 | Martinez, M, Bouillon, A, Batista, F, Alzari, P.M, Barale, J.C, Haouz, A. | 登録日 | 2023-03-01 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.251 Å) | 主引用文献 | 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived alpha-ketoamide inhibitor. Acta Crystallogr D Struct Biol, 79, 2023
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8COZ
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![BU of 8coz by Molmil](/molmil-images/mine/8coz) | Structure of the catalytic domain of P. vivax Sub1 (triclinic crystal form) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SULFATE ION, ... | 著者 | Martinez, M, Bouillon, A, Batista, F, Alzari, P.M, Barale, J.C, Haouz, A. | 登録日 | 2023-03-01 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.438 Å) | 主引用文献 | 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived alpha-ketoamide inhibitor. Acta Crystallogr D Struct Biol, 79, 2023
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8POL
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![BU of 8pol by Molmil](/molmil-images/mine/8pol) | Crystal structure of Plasmodium falciparum Sub1 protease | 分子名称: | CALCIUM ION, PHOSPHATE ION, Subtilisin-like protease 1 | 著者 | Martinez, M, Bouillon, A, Haouz, A, Barale, J.C, Alzari, P.M. | 登録日 | 2023-07-05 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress. Mbio, 15, 2024
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6ZP7
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![BU of 6zp7 by Molmil](/molmil-images/mine/6zp7) | SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Martinez, M, Marabini, R, Carazo, J.M. | 登録日 | 2020-07-08 | 公開日 | 2020-07-29 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures. Iucrj, 7, 2020
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6ZOW
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![BU of 6zow by Molmil](/molmil-images/mine/6zow) | SARS-CoV-2 spike in prefusion state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Martinez, M, Marabini, R, Carazo, J.M. | 登録日 | 2020-07-07 | 公開日 | 2020-07-29 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures. Iucrj, 7, 2020
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6ZP5
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![BU of 6zp5 by Molmil](/molmil-images/mine/6zp5) | SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Martinez, M, Marabini, R, Carazo, J.M. | 登録日 | 2020-07-08 | 公開日 | 2020-07-29 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures. Iucrj, 7, 2020
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5JD3
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![BU of 5jd3 by Molmil](/molmil-images/mine/5jd3) | Crystal structure of LAE5, an alpha/beta hydrolase enzyme from the metagenome of Lake Arreo, Spain | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, LAE5, ... | 著者 | Stogios, P.J, Xu, X, Nocek, B, Cui, H, Yim, V, Martinez-Martinez, M, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | To be published To Be Published
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5JD4
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![BU of 5jd4 by Molmil](/molmil-images/mine/5jd4) | Crystal structure of LAE6 Ser161Ala mutant, an alpha/beta hydrolase enzyme from the metagenome of Lake Arreo, Spain | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, BENZAMIDINE, CHLORIDE ION, ... | 著者 | Stogios, P.J, Xu, X, Alcaide, M, Yim, V, Cui, H, Martinez-Martinez, M, Ferrer, M, Savchenko, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of LAE6 Ser161Ala mutant, an alpha/beta hydrolase enzyme from the metagenome of Lake Arreo, Spain To Be Published
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5JD5
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![BU of 5jd5 by Molmil](/molmil-images/mine/5jd5) | Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy | 分子名称: | CHLORIDE ION, MGS-MilE3 | 著者 | Stogios, P.J, Xu, X, Cui, H, Martinez-Martinez, M, Chernikova, T.N, Golyshin, P.N, Yakimov, M.M, Ferrer, M, Savchenko, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy To Be Published
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5JD6
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![BU of 5jd6 by Molmil](/molmil-images/mine/5jd6) | Crystal structure of MGS-MChE2, an alpha/beta hydrolase enzyme from the metagenome of sediments from the lagoon of Mar Chica, Morocco | 分子名称: | MGS-MChE2 | 著者 | Stogios, P.J, Xu, X, Nocek, B, Yim, V, Cui, H, Martinez-Martinez, M, Golyshin, P.N, Yakima, M.M, Ferrer, M, Savchenko, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.463 Å) | 主引用文献 | Crystal structure of MGS-MChE2, an alpha/beta hydrolase enzyme from the metagenome of sediments from the lagoon of Mar Chica, Morocco To Be Published
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4TR2
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![BU of 4tr2 by Molmil](/molmil-images/mine/4tr2) | Crystal structure of PvSUB1 | 分子名称: | CALCIUM ION, PHOSPHATE ION, Subtilisin-like 1 serine protease | 著者 | Giganti, D, Bouillon, A, Martinez, M, Weber, P, Girard-Blanc, C, Petres, S, Haouz, A, Barale, J.C, Alzari, P.M. | 登録日 | 2014-06-13 | 公開日 | 2014-09-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase. Nat Commun, 5, 2014
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3EY6
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![BU of 3ey6 by Molmil](/molmil-images/mine/3ey6) | Crystal structure of the FK506-binding domain of human FKBP38 | 分子名称: | FK506-binding protein 8 | 著者 | Parthier, C, Maestre-Martinez, M, Neumann, P, Edlich, F, Fischer, G, Luecke, C, Stubbs, M.T. | 登録日 | 2008-10-19 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding. J.Mol.Recognit., 24, 2011
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2F2D
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![BU of 2f2d by Molmil](/molmil-images/mine/2f2d) | Solution structure of the FK506-binding domain of human FKBP38 | 分子名称: | 38 kDa FK-506 binding protein homolog, FKBP38 | 著者 | Maestre-Martinez, M, Edlich, F, Jarczowski, F, Weiwad, M, Fischer, G, Luecke, C. | 登録日 | 2005-11-16 | 公開日 | 2006-05-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the FK506-Binding Domain of Human FKBP38 J.BIOMOL.NMR, 34, 2006
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6YBA
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![BU of 6yba by Molmil](/molmil-images/mine/6yba) | HAdV-F41 Capsid | 分子名称: | Hexon protein, Hexon-interlacing protein, Penton protein, ... | 著者 | Perez Illana, M, Martinez, M, Mangroo, C, Brown, M, Marabini, R, San Martin, C. | 登録日 | 2020-03-16 | 公開日 | 2021-03-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural variations among human adenoviruses. Sci Adv, 7, 2021
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8QKE
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![BU of 8qke by Molmil](/molmil-images/mine/8qke) | PvSub1 Catalytic Domain in Complex with Peptidomimetic Inhibitor (MH-13) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Peptidomimetic Inhibitor (MH-13), ... | 著者 | Batista, F.A, Martinez, M, Bouillon, A, Mechaly, A, Alzari, P.M, Haouz, A, Barale, J.C. | 登録日 | 2023-09-15 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.504 Å) | 主引用文献 | Insights from structure-activity relationships and the binding mode of peptidic alpha-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1. Eur.J.Med.Chem., 269, 2024
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8QKG
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![BU of 8qkg by Molmil](/molmil-images/mine/8qkg) | PvSub1 Catalytic Domain in Complex with Peptidomimetic Inhibitor (MAM-125) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Peptidomimetic Inhibitor (MAM-125), ... | 著者 | Batista, F.A, Martinez, M, Bouillon, A, Mechaly, A, Alzari, P.M, Haouz, A, Barale, J.C. | 登録日 | 2023-09-15 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.538 Å) | 主引用文献 | Insights from structure-activity relationships and the binding mode of peptidic alpha-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1. Eur.J.Med.Chem., 269, 2024
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8QKJ
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![BU of 8qkj by Molmil](/molmil-images/mine/8qkj) | PvSub1 Catalytic Domain in Complex with Peptidomimetic Inhibitor (MAM-133) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Peptidomimetic Inhibitor (MAM-133), ... | 著者 | Batista, F.A, Martinez, M, Bouillon, A, Mechaly, A, Alzari, P.M, Haouz, A, Barale, J.C. | 登録日 | 2023-09-15 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.767 Å) | 主引用文献 | Insights from structure-activity relationships and the binding mode of peptidic alpha-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1. Eur.J.Med.Chem., 269, 2024
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7QDH
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![BU of 7qdh by Molmil](/molmil-images/mine/7qdh) | SARS-CoV-2 S protein S:D614G mutant 1-up | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | 著者 | Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M. | 登録日 | 2021-11-27 | 公開日 | 2022-05-25 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation. Plos Pathog., 18, 2022
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7QDG
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![BU of 7qdg by Molmil](/molmil-images/mine/7qdg) | SARS-CoV-2 S protein S:A222V + S:D614G mutant 1-up | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M. | 登録日 | 2021-11-27 | 公開日 | 2022-05-25 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation. Plos Pathog., 18, 2022
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2KDU
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![BU of 2kdu by Molmil](/molmil-images/mine/2kdu) | Structural basis of the Munc13-1/Ca2+-Calmodulin interaction: A novel 1-26 calmodulin binding motif with a bipartite binding mode | 分子名称: | CALCIUM ION, Calmodulin, Protein unc-13 homolog A | 著者 | Rodriguez-Castaneda, F.A, Maestre-Martinez, M, Coudevylle, N, Dimova, K, Jahn, O, Junge, H, Becker, S, Brose, N, Carlomagno, T, Griesinger, C. | 登録日 | 2009-01-19 | 公開日 | 2009-12-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. Embo J., 29, 2010
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4Q30
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![BU of 4q30 by Molmil](/molmil-images/mine/4q30) | |
6Z0F
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![BU of 6z0f by Molmil](/molmil-images/mine/6z0f) | Crystal structure of the membrane pseudokinase YukC/EssB from Bacillus subtilis T7SS | 分子名称: | ESX secretion system protein YukC | 著者 | Tassinari, M, Bellinzoni, M, Alzari, P.M, Fronzes, R, Gubellini, F. | 登録日 | 2020-05-08 | 公開日 | 2021-05-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | 主引用文献 | The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB. Mbio, 13, 2022
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