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3ENP
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BU of 3enp by Molmil
Crystal structure of human cgi121
分子名称: TP53RK-binding protein
著者Haffani, Y.Z, Ceccarelli, D.F, Neculai, D, Mao, D.Y, Sicheri, F.
登録日2008-09-25
公開日2008-11-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
4K25
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BU of 4k25 by Molmil
Crystal Structure of yeast Qri7 homodimer
分子名称: CALCIUM ION, Probable tRNA threonylcarbamoyladenosine biosynthesis protein QRI7, mitochondrial, ...
著者Neculai, D, Wan, L, Mao, D.Y, Sicheri, F.
登録日2013-04-08
公開日2013-05-08
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.
Nucleic Acids Res., 41, 2013
4JVG
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BU of 4jvg by Molmil
B-Raf Kinase in Complex with Birb796
分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Serine/threonine-protein kinase B-raf
著者Lavoie, H, Thevakumaran, N, Gavory, G, Li, J, Padeganeh, A, Guiral, S, Duchaine, J, Mao, D.Y.L, Bouvier, M, Sicheri, F, Therrien, M.
登録日2013-03-25
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.
Nat.Chem.Biol., 9, 2013
7KJT
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BU of 7kjt by Molmil
KEOPS tRNA modifying sub-complex of archaeal Cgi121 and tRNA
分子名称: RNA (70-MER), Regulatory protein Cgi121
著者Ceccarelli, D.F, Beenstock, J, Mao, D.Y.L, Sicheri, F.
登録日2020-10-26
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献A substrate binding model for the KEOPS tRNA modifying complex.
Nat Commun, 11, 2020
2K8Y
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BU of 2k8y by Molmil
Solution NMR Structure of Cgi121 from Methanococcus jannaschii. Northeast Structural Genomics Consortium Target MJ0187
分子名称: Uncharacterized protein MJ0187
著者Rumpel, S, Fares, C, Neculai, D, Arrowsmith, C, Montelione, G.T, Sicheri, F, Northeast Structural Genomics Consortium (NESG)
登録日2008-09-25
公開日2008-11-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
3EN9
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BU of 3en9 by Molmil
Structure of the Methanococcus jannaschii KAE1-BUD32 fusion protein
分子名称: HEXATANTALUM DODECABROMIDE, MAGNESIUM ION, O-sialoglycoprotein endopeptidase/protein kinase
著者Neculai, D.
登録日2008-09-25
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
3ENO
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BU of 3eno by Molmil
Crystal structure of Pyrococcus furiosus Pcc1 in complex with Thermoplasma acidophilum Kae1
分子名称: MAGNESIUM ION, Putative O-sialoglycoprotein endopeptidase, uncharacterized protein PF2011
著者Neculai, D.
登録日2008-09-25
公開日2008-10-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.0201 Å)
主引用文献Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
3ENC
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BU of 3enc by Molmil
Crystal structure of Pyrococcus furiosus PCC1 dimer
分子名称: protein PCC1
著者Neculai, D.
登録日2008-09-25
公開日2008-10-28
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.6304 Å)
主引用文献Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
3ENH
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BU of 3enh by Molmil
Crystal structure of Cgi121/Bud32/Kae1 complex
分子名称: HEXATANTALUM DODECABROMIDE, Putative O-sialoglycoprotein endopeptidase, Uncharacterized protein MJ0187
著者Neculai, D.
登録日2008-09-25
公開日2008-10-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Atomic Structure of the KEOPS Complex: An Ancient Protein Kinase-Containing Molecular Machine
Mol.Cell, 32, 2008
4O1O
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BU of 4o1o by Molmil
Crystal Structure of RNase L in complex with 2-5A
分子名称: Ribonuclease L, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
著者Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
登録日2013-12-16
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
4O1P
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BU of 4o1p by Molmil
Crystal Structure of RNase L in complex with 2-5A and AMP-PNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonuclease L, ...
著者Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
登録日2013-12-16
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
4DDG
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BU of 4ddg by Molmil
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1
著者Juang, Y.C, Sanches, M, Sicheri, F.
登録日2012-01-18
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2987 Å)
主引用文献OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45, 2012
4DDI
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BU of 4ddi by Molmil
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1
著者Juang, Y.C, Sanches, M, Sicheri, F.
登録日2012-01-18
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.802 Å)
主引用文献OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45, 2012
1MV3
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BU of 1mv3 by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
分子名称: Myc box dependent interacting protein 1
著者Pineda-Lucena, A, Arrowsmith, C.H.
登録日2002-09-24
公開日2003-09-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
1MUZ
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BU of 1muz by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
分子名称: Myc box dependent interacting protein 1
著者Pineda-Lucena, A, Arrowsmith, C.H.
登録日2002-09-24
公開日2003-09-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
1MV0
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BU of 1mv0 by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
分子名称: Myc box-dependent-interacting protein 1, Myc proto-oncogene protein
著者Pineda-Lucena, A, Arrowsmith, C.H.
登録日2002-09-24
公開日2003-09-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
5TWG
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BU of 5twg by Molmil
human MOB1A bound to human MST1 phosphorylated T353 peptide
分子名称: MOB kinase activator 1A, T353 peptide, ZINC ION
著者Xiong, S, Sicheri, F.
登録日2016-11-13
公開日2017-04-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol. Cell Proteomics, 16, 2017
5TWF
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BU of 5twf by Molmil
Regulation of protein interactions by MOB1 phosphorylation
分子名称: MOB kinase activator 1A, ZINC ION
著者Xiong, S, Sicheri, F.
登録日2016-11-13
公開日2017-04-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.136 Å)
主引用文献Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.
Mol. Cell Proteomics, 16, 2017
5TWH
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BU of 5twh by Molmil
human MOB1A bound to MST1 phosphorylated T367 peptide
分子名称: MOB kinase activator 1A, T367 peptide, ZINC ION
著者Xiong, S, Sicheri, F.
登録日2016-11-13
公開日2017-04-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol. Cell Proteomics, 16, 2017
6BXI
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BU of 6bxi by Molmil
X-ray crystal structure of NDR1 kinase domain
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase 38
著者Xiong, S, Sicheri, F.
登録日2017-12-18
公開日2018-08-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.
Structure, 26, 2018
8T6I
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BU of 8t6i by Molmil
Structure of VHH-Fab complex with engineered Crystal Kappa region
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-16
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7I
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BU of 8t7i by Molmil
Structure of the S1CE variant of Fab F1 (FabS1CE-F1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, S1CE variant of Fab F1 heavy chain, ...
著者Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-06-20
公開日2023-11-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7G
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BU of 8t7g by Molmil
Structure of the CK variant of Fab F1 (FabC-F1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CK variant of Fab F1 heavy chain, ...
著者Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-06-20
公開日2023-11-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7F
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BU of 8t7f by Molmil
Structure of the S1 variant of Fab F1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S1 variant of Fab F1 heavy chain, S1 variant of Fab F1 light chain, ...
著者Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-06-20
公開日2023-11-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T9Y
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BU of 8t9y by Molmil
Structure of VHH-Fab complex with engineered Elbow FNQIKG and Crystal Kappa regions
分子名称: DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-26
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024

 

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