6XA1
 
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4V6V
 | | Tetracycline resistance protein Tet(O) bound to the ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Li, W, Atkinson, G.C, Thakor, N.S, Allas, U, Lu, C, Chan, K.Y, Tenson, T, Schulten, K, Wilson, K.S, Hauryliuk, V, Frank, J. | | 登録日 | 2013-02-25 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | | 主引用文献 | Mechanism of tetracycline resistance by ribosomal protection protein Tet(O).
Nat Commun, 4, 2013
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8AOZ
 | | ForT Mutant L24A | | 分子名称: | 1,2-ETHANEDIOL, 4-azanyl-3-[(2~{S},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]-1~{H}-pyrazole-5-carboxylic acid, Beta-ribofuranosylaminobenzene 5'-phosphate synthase, ... | | 著者 | Li, W, Naismith, J.H. | | 登録日 | 2022-08-09 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Experimental and computational snapshots of C-C bond formation in a C-nucleoside synthase.
Open Biology, 13, 2023
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8AP0
 | | ForT Mutant T138V | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-azanyl-1~{H}-pyrazole-3,5-dicarboxylic acid, Beta-ribofuranosylaminobenzene 5'-phosphate synthase, ... | | 著者 | Li, W, Naismith, J.H. | | 登録日 | 2022-08-09 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Experimental and computational snapshots of C-C bond formation in a C-nucleoside synthase.
Open Biology, 13, 2023
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1LCY
 | | Crystal Structure of the Mitochondrial Serine Protease HtrA2 | | 分子名称: | HtrA2 serine protease | | 著者 | Li, W, Srinivasula, S.M, Chai, J, Li, P, Wu, J.W, Zhang, Z, Alnemri, E.S, Shi, Y. | | 登録日 | 2002-04-07 | | 公開日 | 2002-05-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi.
Nat.Struct.Biol., 9, 2002
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7CY8
 | | Crystal Structure of CMD1 in complex with 5mC-DNA and vitamin C | | 分子名称: | 1,2-ETHANEDIOL, ASCORBIC ACID, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), ... | | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
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7CY4
 | | Crystal Structure of CMD1 in apo form | | 分子名称: | CITRIC ACID, FE (III) ION, Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 | | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
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1H3L
 | | N-terminal fragment of SigR from Streptomyces coelicolor | | 分子名称: | RNA POLYMERASE SIGMA FACTOR | | 著者 | Li, W, Stevenson, C.E.M, Burton, N, Jakimowicz, P, Paget, M.S.B, Buttner, M.J, Lawson, D.M, Kleanthous, C. | | 登録日 | 2002-09-10 | | 公開日 | 2002-10-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.375 Å) | | 主引用文献 | Identification and Structure of the Anti-Sigma Factor-Binding Domain of the Disulfide-Stress Regulated Sigma Factor Sigma(R) from Streptomyces Coelicolor
J.Mol.Biol., 323, 2002
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6OLZ
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6OLG
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4HKF
 | | Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION | | 著者 | Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J. | | 登録日 | 2012-10-15 | | 公開日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin
Cell Res., 22, 2012
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6OM7
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2YXR
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2YXQ
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3B9F
 | | 1.6 A structure of the PCI-thrombin-heparin complex | | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, GLYCEROL, Plasma serine protease inhibitor, ... | | 著者 | Li, W, Adams, T.E, Huntington, J.A. | | 登録日 | 2007-11-05 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5C3S
 | | Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-formyluracil (5fU) | | 分子名称: | 1,2-ETHANEDIOL, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde, 2-OXOGLUTARIC ACID, ... | | 著者 | Li, W, Zhang, T, Ding, J. | | 登録日 | 2015-06-17 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
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5C3P
 | | Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG | | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, NICKEL (II) ION, ... | | 著者 | Li, W, Zhang, T, Ding, J. | | 登録日 | 2015-06-17 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
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5C1Q
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5C3Q
 | | Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and thymine (T) | | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, NICKEL (II) ION, ... | | 著者 | Li, W, Zhang, T, Ding, J. | | 登録日 | 2015-06-17 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
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5C3O
 | | Crystal structure of the C-terminal truncated Neurospora crassa T7H (NcT7HdeltaC) in apo form | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Thymine dioxygenase | | 著者 | Li, W, Zhang, T, Ding, J. | | 登録日 | 2015-06-17 | | 公開日 | 2015-10-21 | | 最終更新日 | 2015-12-02 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
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5C3R
 | | Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-hydroxymethyluracil (5hmU) | | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 5-HYDROXYMETHYL URACIL, ... | | 著者 | Li, W, Zhang, T, Ding, J. | | 登録日 | 2015-06-17 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
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1TB6
 | | 2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfonato-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-alpha-L-idopyranuronic acid-(1-4)-methyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Li, W, Johnson, D.J, Esmon, C.T, Huntington, J.A. | | 登録日 | 2004-05-19 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.
Nat.Struct.Mol.Biol., 11, 2004
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2OL2
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7CRQ
 | | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode) | | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | | 登録日 | 2020-08-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
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2HI9
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