8WDR

Crystal structure of BQ.1.1 RBD complexed with human ACE2

Summary for 8WDR

Entry DOI	10.2210/pdb8wdr/pdb
Descriptor	Angiotensin-converting enzyme 2, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	sars-cov-2, bq.1.1, rbd, human ace2, viral protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	244425.98
Authors	Li, W.,Xie, Y. (deposition date: 2023-09-16, release date: 2024-07-24)
Primary citation	Li, W.,Xu, Z.,Niu, T.,Xie, Y.,Zhao, Z.,Li, D.,He, Q.,Sun, W.,Shi, K.,Guo, W.,Chang, Z.,Liu, K.,Fan, Z.,Qi, J.,Gao, G.F. Key mechanistic features of the trade-off between antibody escape and host cell binding in the SARS-CoV-2 Omicron variant spike proteins. Embo J., 43:1484-1498, 2024 Cited by PubMed: 38467833 DOI: 10.1038/s44318-024-00062-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.47 Å)

Structure validation