3B9F
1.6 A structure of the PCI-thrombin-heparin complex
Summary for 3B9F
Entry DOI | 10.2210/pdb3b9f/pdb |
Related | 2HI9 2OL2 |
Descriptor | Prothrombin, Plasma serine protease inhibitor, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | michaelis complex, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, secreted, serine protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 81646.57 |
Authors | Li, W.,Adams, T.E.,Huntington, J.A. (deposition date: 2007-11-05, release date: 2008-04-22, Last modification date: 2023-11-01) |
Primary citation | Li, W.,Adams, T.E.,Nangalia, J.,Esmon, C.T.,Huntington, J.A. Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex. Proc.Natl.Acad.Sci.Usa, 105:4661-4666, 2008 Cited by PubMed: 18362344DOI: 10.1073/pnas.0711055105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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