8WE4

SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304

Summary for 8WE4

Entry DOI	10.2210/pdb8we4/pdb
EMDB information	37471
Descriptor	Angiotensin-converting enzyme 2, Spike protein S1, S304 Fab Heavy Chain, ... (8 entities in total)
Functional Keywords	rbd, viral protein, virus, virus-immune system complex, virus/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	167954.08
Authors	Li, W.,Xie, Y. (deposition date: 2023-09-17, release date: 2024-07-24)
Primary citation	Li, W.,Xu, Z.,Niu, T.,Xie, Y.,Zhao, Z.,Li, D.,He, Q.,Sun, W.,Shi, K.,Guo, W.,Chang, Z.,Liu, K.,Fan, Z.,Qi, J.,Gao, G.F. Key mechanistic features of the trade-off between antibody escape and host cell binding in the SARS-CoV-2 Omicron variant spike proteins. Embo J., 43:1484-1498, 2024 Cited by PubMed: 38467833 DOI: 10.1038/s44318-024-00062-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.91 Å)

Structure validation