1UZK
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![BU of 1uzk by Molmil](/molmil-images/mine/1uzk) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Ca bound to cbEGF23 domain only | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-13 | 公開日 | 2006-05-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1UZP
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![BU of 1uzp by Molmil](/molmil-images/mine/1uzp) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Sm bound form cbEGF23 domain only. | 分子名称: | FIBRILLIN-1, SAMARIUM (III) ION | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-15 | 公開日 | 2004-04-08 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1UZJ
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![BU of 1uzj by Molmil](/molmil-images/mine/1uzj) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form. | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-12 | 公開日 | 2004-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1UZQ
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![BU of 1uzq by Molmil](/molmil-images/mine/1uzq) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23 domain only. | 分子名称: | FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-15 | 公開日 | 2004-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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8K7C
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![BU of 8k7c by Molmil](/molmil-images/mine/8k7c) | Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION, ... | 著者 | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | 登録日 | 2023-07-26 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol, 6, 2023
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8K7B
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![BU of 8k7b by Molmil](/molmil-images/mine/8k7b) | post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound) | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ATP-binding cassette sub-family B member 6, ... | 著者 | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | 登録日 | 2023-07-26 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol, 6, 2023
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8YR4
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![BU of 8yr4 by Molmil](/molmil-images/mine/8yr4) | Cryo-EM structure of the human ABCB6 in complex with Cd(II):Phytochelatin 2 | 分子名称: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GAMMA-D-GLUTAMIC ACID, ... | 著者 | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | 登録日 | 2024-03-20 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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8YR3
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![BU of 8yr3 by Molmil](/molmil-images/mine/8yr3) | Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH | 分子名称: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE | 著者 | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | 登録日 | 2024-03-20 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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3VPS
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![BU of 3vps by Molmil](/molmil-images/mine/3vps) | Structure of a novel NAD dependent-NDP-hexosamine 5,6-dehydratase, TunA, involved in tunicamycin biosynthesis | 分子名称: | NAD-dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | 著者 | Wyszynski, F.J, Lee, S.S, Yabe, T, Wang, H, Gomez-Escribano, J.P, Bibb, M.J, Lee, S.J, Davies, G.J, Davis, B.G. | 登録日 | 2012-03-12 | 公開日 | 2012-04-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Biosynthesis of nucleoside antibiotic tunicamycin proceeds via unique exo-glycal intermediates To be published
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5I3D
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![BU of 5i3d by Molmil](/molmil-images/mine/5i3d) | Sulfolobus solfataricus beta-glycosidase - E387Y mutant | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, Beta-galactosidase | 著者 | Iglesias-Fernandez, J, Hancock, S.M, Lee, S.S, McAuley, K.E, Fordham-Skelton, A, Rovira, C, Davis, B.D. | 登録日 | 2016-02-10 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase. Nat. Chem. Biol., 13, 2017
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1XSI
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![BU of 1xsi by Molmil](/molmil-images/mine/1xsi) | Structure of a Family 31 alpha glycosidase | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ACETIC ACID, Putative family 31 glucosidase yicI, ... | 著者 | Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C. | 登録日 | 2004-10-19 | 公開日 | 2004-10-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic and Structural Analysis of a Family 31 alpha-Glycosidase and Its Glycosyl-enzyme Intermediate J.Biol.Chem., 280, 2005
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1XDP
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![BU of 1xdp by Molmil](/molmil-images/mine/1xdp) | Crystal Structure of the E.coli Polyphosphate Kinase in complex with AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyphosphate kinase | 著者 | Zhu, Y, Huang, W, Lee, S.S, Xu, W. | 登録日 | 2004-09-07 | 公開日 | 2005-06-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a polyphosphate kinase and its implications for polyphosphate synthesis Embo Rep., 6, 2005
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1XSJ
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![BU of 1xsj by Molmil](/molmil-images/mine/1xsj) | Structure of a Family 31 alpha glycosidase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Putative family 31 glucosidase yicI | 著者 | Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C. | 登録日 | 2004-10-19 | 公開日 | 2004-10-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanistic and Structural Analysis of a Family 31 alpha-Glycosidase and Its Glycosyl-enzyme Intermediate J.Biol.Chem., 280, 2005
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1XSK
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![BU of 1xsk by Molmil](/molmil-images/mine/1xsk) | Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 5(R)-fluoro-beta-D-xylopyranose, Putative family 31 glucosidase yicI, ... | 著者 | Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C. | 登録日 | 2004-10-19 | 公開日 | 2004-11-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic and Structural Analysis of a Family 31 {alpha}-Glycosidase and Its Glycosyl-enzyme Intermediate J.Biol.Chem., 280, 2005
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1XDO
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![BU of 1xdo by Molmil](/molmil-images/mine/1xdo) | |
7DNZ
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![BU of 7dnz by Molmil](/molmil-images/mine/7dnz) | Cryo-EM structure of the human ABCB6 (Hemin and GSH-bound) | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Kim, S, Lee, S.S, Park, J.G, Kim, J.W, Kim, S, Kim, N.J, Hong, S, Kang, J.Y, Jin, M.S. | 登録日 | 2020-12-11 | 公開日 | 2022-06-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. Mol.Cells, 45, 2022
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7DNY
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![BU of 7dny by Molmil](/molmil-images/mine/7dny) | Cryo-EM structure of the human ABCB6 (coproporphyrin III-bound) | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Kim, S, Lee, S.S, Park, J.G, Kim, J.W, Kim, S, Kim, N.J, Hong, S, Kang, J.Y, Jin, M.S. | 登録日 | 2020-12-11 | 公開日 | 2022-06-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. Mol.Cells, 45, 2022
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2WTX
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![BU of 2wtx by Molmil](/molmil-images/mine/2wtx) | Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase | 分子名称: | 1,2-ETHANEDIOL, ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING], ... | 著者 | Errey, J.C, Lee, S.S, Gibson, R.P, Martinez-Fleites, C, Barry, C.S, Jung, P.M.J, OSullivan, A, Davis, B.G, Davies, G.J. | 登録日 | 2009-09-25 | 公開日 | 2010-02-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic Insight Into Enzymatic Glycosyl Transfer with Retention of Configuration Through Analysis of Glycomimetic Inhibitors. Angew.Chem.Int.Ed.Engl., 49, 2010
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4OCZ
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![BU of 4ocz by Molmil](/molmil-images/mine/4ocz) | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea | 分子名称: | 1-[1-(2-methylpropanoyl)piperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morriseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | 登録日 | 2014-01-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J.Med.Chem., 57, 2014
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4OD0
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![BU of 4od0 by Molmil](/molmil-images/mine/4od0) | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea | 分子名称: | 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morisseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | 登録日 | 2014-01-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J.Med.Chem., 57, 2014
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6EQL
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![BU of 6eql by Molmil](/molmil-images/mine/6eql) | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP | 分子名称: | 1,2-ETHANEDIOL, Glycogenin-1, MANGANESE (II) ION, ... | 著者 | Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W. | 登録日 | 2017-10-13 | 公開日 | 2017-12-20 | 最終更新日 | 2018-11-14 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis. Nature, 563, 2018
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6EQJ
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![BU of 6eqj by Molmil](/molmil-images/mine/6eqj) | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form | 分子名称: | 1,2-ETHANEDIOL, Glycogenin-1 | 著者 | Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W. | 登録日 | 2017-10-13 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis. Nature, 563, 2018
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6FWZ
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![BU of 6fwz by Molmil](/molmil-images/mine/6fwz) | Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with UDP-GlcNAc | 分子名称: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, ... | 著者 | Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-07 | 公開日 | 2018-07-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design. Cell, 175, 2018
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6FM9
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![BU of 6fm9 by Molmil](/molmil-images/mine/6fm9) | Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) | 分子名称: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | 著者 | Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2018-01-30 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design. Cell, 175, 2018
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5LEV
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![BU of 5lev by Molmil](/molmil-images/mine/5lev) | Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) | 分子名称: | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, UNKNOWN LIGAND | 著者 | Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-30 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design. Cell, 175, 2018
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