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6TLH
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BU of 6tlh by Molmil
Crystal structure of mouse KANK3 ankyrin repeats
分子名称: FORMIC ACID, GLYCEROL, KN motif and ankyrin repeat domain-containing protein 3
著者Khan, R, Singh, A.K, Goult, B.T.
登録日2019-12-02
公開日2020-12-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of mouse KANK3 ankyrin repeats
To be published
6TMD
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BU of 6tmd by Molmil
Crystal structure of KANK2 ankyrin repeats mutant (A670V)
分子名称: ACETATE ION, GLYCEROL, KN motif and ankyrin repeat domain-containing protein 2
著者Khan, R, Singh, A.K, Goult, B.T.
登録日2019-12-04
公開日2020-12-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of KANK2 ankyrin repeats mutant (A670V)
To be published
1R8T
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BU of 1r8t by Molmil
Solution structures of high affinity miniprotein ligands to Streptavidin
分子名称: MP1
著者Luo, J, Mukherjee, M, Fan, X, Yang, H, Liu, D, Khan, R, White, M, Fox, R.O.
登録日2003-10-28
公開日2005-02-15
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structure-based design of high affinity miniprotein ligands
To be Published
5UQC
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BU of 5uqc by Molmil
Crystal structure of mouse CRMP2
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Dihydropyrimidinase-related protein 2
著者Khanna, M, Khanna, R, Perez-Miller, S, Francois-Moutal, L.
登録日2017-02-07
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.
Channels (Austin), 11, 2017
3BW9
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BU of 3bw9 by Molmil
Crystal Structure of HLA B*3508 in complex with a HCMV 12-mer peptide from the pp65 protein
分子名称: Beta-2-microglobulin, CPS peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
著者Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
登録日2008-01-08
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
3BWA
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BU of 3bwa by Molmil
Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein
分子名称: Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
著者Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
登録日2008-01-08
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
6P9E
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BU of 6p9e by Molmil
Crystal structure of IL-36gamma complexed to A-552
分子名称: (2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic acid, Interleukin-36 gamma
著者Argiriadi, M.A, Todorovic, T, Su, Z, Putman, B, Kakavas, S.J, Salte, K.M, McDonald, H.A, Wetter, J.B, Paulsboe, S.E, Sun, Q, Gerstein, C.E, Medina, L, Sielaff, B, Sadhukhan, R, Stockmann, H, Richardson, P.L, Qiu, W, Henry, R.F, Herold, J.M, Shotwell, J.B, McGaraughty, S.P, Honore, P, Gopalakrishnan, S.M, Sun, C.C, Scott, V.E.
登録日2019-06-10
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Small Molecule IL-36 gamma Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Sci Rep, 9, 2019
3MV9
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BU of 3mv9 by Molmil
Crystal Structure of the TK3-Gln55Ala TCR in complex with HLA-B*3501/HPVG
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
登録日2010-05-03
公開日2010-06-09
最終更新日2011-07-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
3MV7
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BU of 3mv7 by Molmil
Crystal Structure of the TK3 TCR in complex with HLA-B*3501/HPVG
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
登録日2010-05-03
公開日2010-06-09
最終更新日2011-07-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
3MV8
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BU of 3mv8 by Molmil
Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
登録日2010-05-03
公開日2010-06-09
最終更新日2011-07-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
6KI9
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BU of 6ki9 by Molmil
Apo structure of FabMG, novel types of Enoyl-acyl carrier protein reductase
分子名称: 1,2-ETHANEDIOL, FabMG, novel types of Enoyl-acyl carrier protein reductase, ...
著者Kim, S, Rhee, S.
登録日2019-07-17
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献A triclosan-resistance protein from the soil metagenome is a novel enoyl-acyl carrier protein reductase: Structure-guided functional analysis.
Febs J., 287, 2020
2G6U
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BU of 2g6u by Molmil
Solution structures of MP-2: a high affinity miniprotein ligand to Streptavidin
分子名称: Miniprotein MP2
著者Fox, R.O, Mukherjee, M.
登録日2006-02-25
公開日2007-04-10
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural studies of high affinity miniprotein ligands to Streptavidin
To be Published
6KIA
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BU of 6kia by Molmil
NADH bound structure of FabMG, novel type of Enoyl-acyl carrier protein reductase
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-acyl carrier protein reductase
著者Kim, S, Rhee, S.
登録日2019-07-17
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.59798265 Å)
主引用文献A triclosan-resistance protein from the soil metagenome is a novel enoyl-acyl carrier protein reductase: Structure-guided functional analysis.
Febs J., 287, 2020
5DPX
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BU of 5dpx by Molmil
1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases.
分子名称: 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, Metallo-beta-lactamase L1 type 3, SULFATE ION, ...
著者Nauton, L, Garau, G, Khan, R, Dideberg, O.
登録日2015-09-14
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases.
ChemMedChem, 12, 2017
6PE7
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BU of 6pe7 by Molmil
Crystal Structure of ABBV-323 FAB
分子名称: FAB Heavy Chain, FAB Light chain, SULFATE ION
著者Argiriadi, M.A.
登録日2019-06-20
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches.
BMC Mol Cell Biol, 20, 2019
6PE9
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Crystal Structure of CD40 complexed to FAB516
分子名称: FAB Heavy chain, FAB Light chain, SULFATE ION, ...
著者Argiriadi, M.A.
登録日2019-06-20
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches.
BMC Mol Cell Biol, 20, 2019
6PE8
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BU of 6pe8 by Molmil
Crystal structure of CD40/ABBV-323 FAB complex
分子名称: FAB Heavy chain, FAB Light chain, SULFATE ION, ...
著者Argiriadi, M.A.
登録日2019-06-20
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches.
BMC Mol Cell Biol, 20, 2019
4QRT
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BU of 4qrt by Molmil
Crystal Structure of HLA B*0801 in complex with ELN_YYM, ELNRKMIYM
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Gras, S, Twist, K.-A, Rossjohn, J.
登録日2014-07-02
公開日2014-07-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
4QRU
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BU of 4qru by Molmil
Crystal Structure of HLA B*0801 in complex with ELR_MYM, ELRRKMMYM
分子名称: 55 kDa immediate-early protein 1, ACETATE ION, Beta-2-microglobulin, ...
著者Gras, S, Twist, K.-A, Rossjohn, J.
登録日2014-07-02
公開日2015-02-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
8QEO
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BU of 8qeo by Molmil
cryo-EM structure complex of Frizzled-7 and Clostridioides difficile toxin B
分子名称: Frizzled-7, Toxin B, ZINC ION
著者Kinsolving, J, Bous, J.
登録日2023-09-01
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD 7.
Cell Rep, 43, 2024
8QEN
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BU of 8qen by Molmil
cryo-EM structure of apo Clostridioides difficile toxin B
分子名称: Toxin B, ZINC ION
著者Kinsolving, J, Bous, J, Structural Genomics Consortium (SGC)
登録日2023-09-01
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD 7.
Cell Rep, 43, 2024
7TLT
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BU of 7tlt by Molmil
SARS-CoV-2 Spike-derived peptide S489-497 (YFPLQSYGF) presented by HLA-A*29:02
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
著者Murdolo, L.D, Szeto, C, Gras, S.
登録日2022-01-18
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ablation of CD8 + T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3.
Nat Commun, 13, 2022
3KA0
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MK2 complex with inhibitor 6-(5-(2-aminopyrimidin-4-ylamino)-2-hydroxyphenyl)-N-methylbenzo[b]thiophene-2-carboxamide
分子名称: 6-{5-[(2-aminopyrimidin-4-yl)amino]-2-hydroxyphenyl}-N-methylidene-1-benzothiophene-2-carboxamide, MAP kinase-activated protein kinase 2
著者Argiriadi, M.A, Talanian, R.V, Borhani, D.W.
登録日2009-10-16
公開日2010-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode.
Bioorg.Med.Chem.Lett., 20, 2010
3KC3
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MK2 complexed to inhibitor N4-(7-(benzofuran-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine
分子名称: MAP kinase-activated protein kinase 2, N~4~-[7-(1-benzofuran-2-yl)-1H-indazol-5-yl]pyrimidine-2,4-diamine
著者Argiriadi, M.A, Talanian, R.V, Borhani, D.W.
登録日2009-10-20
公開日2010-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode.
Bioorg.Med.Chem.Lett., 20, 2010
3KXF
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BU of 3kxf by Molmil
Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Archbold, J.K, Tynan, F.E, Gras, S, Rossjohn, J.
登録日2009-12-03
公開日2010-06-09
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
Proc.Natl.Acad.Sci.USA, 107, 2010

 

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